Ergotamine/caffeine
| Combination of | |
|---|---|
| Ergotamine | vasoconstrictor, neurotransmitter agonist and antagonist |
| Caffeine | vasoconstrictor, phosphodiesterase inhibitor |
| Clinical data | |
| Trade names | Cafergot, Migergot, others |
| AHFS/Drugs.com | Multum Consumer Information |
| MedlinePlus | a601048 |
| License data | |
| Pregnancy category |
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| Routes of administration | By mouth, rectal |
| ATC code | |
| Legal status | |
| Legal status | |
| Identifiers | |
| CAS Number | |
| KEGG | |
Ergotamine/caffeine, sold under the brand name Cafergot among others, is a fixed-dose combination medication used for the treatment of migraine. It contains ergotamine, as the tartrate, an alpha adrenergic blocking agent; and caffeine, a cranial vasoconstrictor.[3]
Ergotamine/caffeine is available as a generic medication.
- ^ "Cafergot- ergotamine tartrate and caffeine tablet, film coated". DailyMed. U.S. National Library of Medicine. Archived from the original on 16 January 2014.
- ^ "Migergot- ergotamine tartrate and caffeine suppository". DailyMed. 29 November 2022. Retrieved 18 May 2024.
- ^ Diener HC, Jansen JP, Reches A, Pascual J, Pitei D, Steiner TJ (2002). "Efficacy, tolerability and safety of oral eletriptan and ergotamine plus caffeine (Cafergot) in the acute treatment of migraine: a multicentre, randomised, double-blind, placebo-controlled comparison". European Neurology. 47 (2): 99–107. doi:10.1159/000047960. PMID 11844898. S2CID 72629130.