Fazio–Londe disease

Fazio–Londe disease
Other namesProgressive bulbar palsy of childhood
This condition has an autosomal recessive mode of inheritance
SpecialtyNeurology 

Fazio–Londe disease (FLD), also called progressive bulbar palsy of childhood,[1][2] is a very rare inherited motor neuron disease of children and young adults and is characterized by progressive paralysis of muscles innervated by cranial nerves. FLD, along with Brown–Vialetto–Van Laere syndrome (BVVL), are the two forms of infantile progressive bulbar palsy,[3] a type of progressive bulbar palsy in children.

  1. ^ Online Mendelian Inheritance in Man (OMIM): 211500
  2. ^ McShane, MA; Boyd, S; Harding, B; Brett, EM; Wilson, J (December 1992). "Progressive bulbar paralysis of childhood. A reappraisal of Fazio-Londe disease". Brain: A Journal of Neurology. 115 (Pt 6): 1889–900. doi:10.1093/brain/115.6.1889. PMID 1486466.
  3. ^ Piña-Garza, J. Eric (2013). Fenichel's Clinical Pediatric Neurology E-Book: A Signs and Symptoms Approach. Elsevier Health Sciences. p. 328. ISBN 978-1455748129. Retrieved 5 December 2017.