Fibrous cap

The fibrous cap is a layer of fibrous connective tissue, which is thicker and less cellular than the normal intima, found in atheromatous plaques. The fibrous cap contains macrophages and smooth muscle cells.[1] The fibrous cap of an atheroma is composed of bundles of muscle cells, macrophages, foam cells, lymphocytes, collagen and elastin.[1] An atheroma with a cap is termed a fibrous cap atheroma.

  1. ^ a b Hansson, Göran K.; Libby, Peter (July 2006). "The immune response in atherosclerosis: a double-edged sword". Nature Reviews Immunology. 6 (7): 508–519. doi:10.1038/nri1882. PMID 16778830.
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