Florfenicol

Florfenicol
Clinical data
Trade names	Nuflor
Other names	2,2-dichloro-N-((1R,2S)-3-fluoro-1-hydroxy-1-(4-(methylsulfonyl)phenyl)propan-2-yl)ethanamide
AHFS/Drugs.com	International Drug Names
Routes of; administration	Intramuscular, subcutaneous
ATCvet code	QJ01BA90 (WHO) QJ51BA90 (WHO);
Legal status
Legal status	AU: S4 (Prescription only); US: ℞-only;
Identifiers
	IUPAC name 2,2-dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methanesulfonylphenyl)propan-2-yl]acetamide;
CAS Number	73231-34-2 ;
PubChem CID	114811;
ChemSpider	102776 ;
UNII	9J97307Y1H;
KEGG	D04194 ;
ChEBI	CHEBI:87185 ;
ChEMBL	ChEMBL1241590 ;
CompTox Dashboard (EPA)	DTXSID9045500 ;
ECHA InfoCard	100.170.898
Chemical and physical data
Formula	C12H14Cl2FNO4S
Molar mass	358.21 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES ClC(Cl)C(=O)N[C@@H]([C@H](O)c1ccc(cc1)S(=O)(=O)C)CF;
	InChI InChI=1S/C12H14Cl2FNO4S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-15)16-12(18)11(13)14/h2-5,9-11,17H,6H2,1H3,(H,16,18)/t9-,10-/m1/s1 ; Key:AYIRNRDRBQJXIF-NXEZZACHSA-N ;
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Florfenicol (marketed by Schering-Plough Animal Health under the brand name Nuflor) is a fluorinated synthetic analog of thiamphenicol,^[1] mainly used as a antibiotic in veterinary medicine.

Florfenicol is available a generic medication.^[2]

^ Syriopoulou VP, Harding AL, Goldmann DA, Smith AL (February 1981). "In vitro antibacterial activity of fluorinated analogs of chloramphenicol and thiamphenicol". Antimicrobial Agents and Chemotherapy. 19 (2): 294–297. doi:10.1128/aac.19.2.294. PMC 181412. PMID 6957162.
^ "Florfenicol". Drugs.com.

[1] Syriopoulou VP, Harding AL, Goldmann DA, Smith AL (February 1981). "In vitro antibacterial activity of fluorinated analogs of chloramphenicol and thiamphenicol". Antimicrobial Agents and Chemotherapy. 19 (2): 294–297. doi:10.1128/aac.19.2.294. PMC 181412. PMID 6957162.

[2] "Florfenicol". Drugs.com.

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