GSD microscopy

Ground state depletion microscopy (GSD microscopy) is an implementation of the RESOLFT concept. The method was proposed in 1995[1] and experimentally demonstrated in 2007.[2] It is the second concept to overcome the diffraction barrier in far-field optical microscopy published by Stefan Hell. Using nitrogen-vacancy centers in diamonds a resolution of up to 7.8 nm was achieved in 2009.[3] This is far below the diffraction limit (~200 nm).

  1. ^ Stefan W. Hell M. Kroug (1995). "Ground-state-depletion fluorescence microscopy: a concept for breaking the diffraction resolution limit". Applied Physics B: Lasers and Optics. 60 (5): 495–497. Bibcode:1995ApPhB..60..495H. doi:10.1007/BF01081333.
  2. ^ Stefan Bretschneider; Christian Eggeling; Stefan W. Hell (2007). "Breaking the diffraction barrier in fluorescence microscopy by optical shelving". Physical Review Letters. 98 (5): 218103. Bibcode:2007PhRvL..98u8103B. doi:10.1103/PhysRevLett.98.218103. hdl:11858/00-001M-0000-0012-E125-B. PMID 17677813.
  3. ^ Eva Rittweger; Dominik Wildanger; Stefan W. Hell (2009). "Far-field fluorescence nanoscopy of diamond color centers by ground state depletion" (PDF). EPL. 86 (1): 14001. Bibcode:2009EL.....8614001R. doi:10.1209/0295-5075/86/14001.
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