Glutaraldehyde

Glutaraldehyde
Names
	Preferred IUPAC name Pentanedial
	Other names Glutaraldehyde; Glutardialdehyde; Glutaric acid dialdehyde; Glutaric aldehyde; Glutaric dialdehyde; 1,5-Pentanedial
Identifiers
CAS Number	111-30-8 ;
3D model (JSmol)	Interactive image;
ChemSpider	3365 ;
DrugBank	DB03266 ;
ECHA InfoCard	100.003.506
KEGG	D01120 ;
PubChem CID	3485;
UNII	T3C89M417N ;
CompTox Dashboard (EPA)	DTXSID6025355 ;
	InChI InChI=1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2 Key: SXRSQZLOMIGNAQ-UHFFFAOYSA-N ; InChI=1/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2 Key: SXRSQZLOMIGNAQ-UHFFFAOYAO;
	SMILES O=CCCCC=O;
Properties
Chemical formula	C5H8O2
Molar mass	100.117
Appearance	Clear liquid
Odor	pungent
Density	1.06 g/mL
Melting point	−14 °C (7 °F; 259 K)
Boiling point	187 °C (369 °F; 460 K)
Solubility in water	Miscible, reacts
Vapor pressure	17 mmHg (20°C)
Hazards
	GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H302, H314, H317, H331, H334, H400
Precautionary statements	P260, P264, P270, P271, P272, P273, P280, P284, P301+P312, P302+P352, P304+P340, P305+P351+P338, P311, P330, P332+P313, P403+P233, P405, P501
NFPA 704 (fire diamond)	2 2 0
Flash point	noncombustible
Threshold limit value (TLV)	0.2 ppm (0.82 mg/m3) (TWA), 0.05 ppm (STEL)
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	134 mg/kg (rat, oral); 2,560 mg/kg (rabbit, dermal)
	NIOSH (US health exposure limits):
REL (Recommended)	0.2 ppm (0.8 mg/m3)
Safety data sheet (SDS)	CAS 111-30-8
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Glutaraldehyde is an organic compound with the formula (CH₂)₃(CHO)₂. The molecule consists of a five carbon chain doubly terminated with formyl (CHO) groups. It is usually used as a solution in water, and such solutions exists as a collection of hydrates, cyclic derivatives, and condensation products, several of which interconvert. Because the molecule has two aldehyde functional groups, glutaraldehyde (and its hydrates) can crosslink substances with primary amine groups, through condensation. Crosslinking can rigidify and deactivate proteins and other molecules that are critical for normal biological function, such as DNA, and so glutaraldehyde solutions are effective biocides and fixatives. It is sold under the brandnames Cidex and Glutaral.^[3]^[4]^[5]^[6] As a disinfectant, it is used to sterilize surgical instruments.^[3]

^ Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. p. 907. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4.
^ ^a ^b ^c ^d "CDC - NIOSH Pocket Guide to Chemical Hazards -Glutaraldehyde". www.cdc.gov. Archived from the original on 13 January 2017. Retrieved 11 January 2017.
^ ^a ^b World Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. pp. 323, 325. hdl:10665/44053. ISBN 9789241547659.
^ British national formulary : BNF 69 (69 ed.). British Medical Association. 2015. p. 825. ISBN 9780857111562.
^ Bonewit-West, Kathy (2015). Clinical Procedures for Medical Assistants. Elsevier Health Sciences. p. 96. ISBN 9781455776610. Archived from the original on 6 October 2022. Retrieved 9 September 2017.
^ Sullivan, John Burke; Krieger, Gary R. (2001). Clinical Environmental Health and Toxic Exposures. Lippincott Williams & Wilkins. p. 601. ISBN 9780683080278. Archived from the original on 10 October 2022. Retrieved 19 September 2020.

[RSC-2014-1] Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. p. 907. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4.

[CDC-2] "CDC - NIOSH Pocket Guide to Chemical Hazards -Glutaraldehyde". www.cdc.gov. Archived from the original on 13 January 2017. Retrieved 11 January 2017.

[WHO-2009-3] World Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. pp. 323, 325. hdl:10665/44053. ISBN 9789241547659.

[BMA-2015-4] British national formulary : BNF 69 (69 ed.). British Medical Association. 2015. p. 825. ISBN 9780857111562.

[5] Bonewit-West, Kathy (2015). Clinical Procedures for Medical Assistants. Elsevier Health Sciences. p. 96. ISBN 9781455776610. Archived from the original on 6 October 2022. Retrieved 9 September 2017.

[6] Sullivan, John Burke; Krieger, Gary R. (2001). Clinical Environmental Health and Toxic Exposures. Lippincott Williams & Wilkins. p. 601. ISBN 9780683080278. Archived from the original on 10 October 2022. Retrieved 19 September 2020.

[1]

[2]

[3]

[4]

[5]

[6]