Glycolic acid

Glycolic acid
Names
Preferred IUPAC name
Hydroxyacetic acid
Other names
Hydroacetic acid
2-Hydroxyethanoic acid
Identifiers
CAS Number
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
DrugBank
ECHA InfoCard 100.001.073
EC Number
  • 201-180-5
KEGG
PubChem CID
RTECS number
  • MC5250000
UNII
InChI
  • InChI=1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5) Y
    Key: AEMRFAOFKBGASW-UHFFFAOYSA-N Y
  • InChI=1/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)
    Key: AEMRFAOFKBGASW-UHFFFAOYAR
SMILES
  • OC(=O)CO
Properties
Chemical formula
C2H4O3
Molar mass 76.05 g/mol
Appearance White powder or colorless crystals
Density 1.49 g/cm3[1]
Melting point 75 °C (167 °F; 348 K)
Boiling point 100 °C (212 °F; 373 K) Decomposes above 100 °C
Solubility in water
70% solution
Solubility in other solvents Alcohols, acetone,
acetic acid and
ethyl acetate[2]
log P −1.05[3]
Vapor pressure 1.051 kPa (80 °C)
Acidity (pKa) 3.83
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
Corrosive
GHS labelling:
Pictograms
Signal word
Danger
Hazard statements
H302, H314, H332
Precautionary statements
P260, P261, P264, P270, P271, P280, P301+P312, P301+P330+P331, P303+P361+P353, P304+P312, P304+P340, P305+P351+P338, P310, P312, P321, P330, P363, P405, P501
NFPA 704 (fire diamond)
3
1
1
Flash point 300 °C (572 °F; 573 K)[4]
Lethal dose or concentration (LD, LC):
1950 mg/kg (rat, oral)
2040 mg/kg (rat, oral)
7.7 ppm (rat, 4h)
3.6 ppm (rat, 4h)
Related compounds
Related α-hydroxy acids
Lactic acid
Related compounds
Glycolaldehyde
Acetic acid
Glycerol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Glycolic acid (or hydroxyacetic acid; chemical formula HOCH2CO2H) is a colorless, odorless and hygroscopic crystalline solid, highly soluble in water. It is used in various skin-care products. Glycolic acid is widespread in nature. A glycolate (sometimes spelled "glycollate") is a salt or ester of glycolic acid.

  1. ^ United States National Library of Medicine "Hydroxyacetic Acid" in TOXNET Hazardous Substances Data Bank (HSDB), citing Gerhartz, W. (exec ed.), Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA13 509.
  2. ^ "DuPont Glycolic Acid Technical Information". Archived from the original on 2006-07-14. Retrieved 2006-07-06.
  3. ^ "Glycolic acid". www.chemsrc.com. Archived from the original on 2020-07-27. Retrieved 2018-05-16.
  4. ^ "Glycolic Acid MSDS". University of Akron. Retrieved 2006-09-18.