Glycolic acid
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| Names | |||
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| Preferred IUPAC name
Hydroxyacetic acid | |||
| Other names
Hydroacetic acid
2-Hydroxyethanoic acid | |||
| Identifiers | |||
CAS Number
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3D model (JSmol)
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| ChEBI | |||
| ChEMBL | |||
| ChemSpider | |||
| DrugBank | |||
| ECHA InfoCard | 100.001.073 | ||
| EC Number |
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| KEGG | |||
PubChem CID
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CompTox Dashboard (EPA)
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InChI
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SMILES
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| Properties | |||
Chemical formula
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C2H4O3 | ||
| Molar mass | 76.05 g/mol | ||
| Appearance | White powder or colorless crystals | ||
| Density | 1.49 g/cm3[1] | ||
| Melting point | 75 °C (167 °F; 348 K) | ||
| Boiling point | 100 °C (212 °F; 373 K) Decomposes above 100 °C | ||
Solubility in water
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70% solution | ||
| Solubility in other solvents | Alcohols, acetone, acetic acid and ethyl acetate[2] | ||
| log P | −1.05[3] | ||
| Vapor pressure | 1.051 kPa (80 °C) | ||
| Acidity (pKa) | 3.83 | ||
| Hazards | |||
| Occupational safety and health (OHS/OSH): | |||
Main hazards
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Corrosive | ||
| GHS labelling: | |||
Pictograms
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Signal word
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Danger | ||
Hazard statements
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H302, H314, H332 | ||
Precautionary statements
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P260, P261, P264, P270, P271, P280, P301+P312, P301+P330+P331, P303+P361+P353, P304+P312, P304+P340, P305+P351+P338, P310, P312, P321, P330, P363, P405, P501 | ||
| NFPA 704 (fire diamond) | |||
| Flash point | 300 °C (572 °F; 573 K)[4] | ||
| Lethal dose or concentration (LD, LC): | |||
LD50 (median dose)
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1950 mg/kg (rat, oral) 2040 mg/kg (rat, oral) | ||
LC50 (median concentration)
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7.7 ppm (rat, 4h) 3.6 ppm (rat, 4h) | ||
| Related compounds | |||
Related α-hydroxy acids
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Lactic acid | ||
Related compounds
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Glycolaldehyde Acetic acid Glycerol | ||
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
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Glycolic acid (or hydroxyacetic acid; chemical formula HOCH2CO2H) is a colorless, odorless and hygroscopic crystalline solid, highly soluble in water. It is used in various skin-care products. Glycolic acid is widespread in nature. A glycolate (sometimes spelled "glycollate") is a salt or ester of glycolic acid.
- ^ United States National Library of Medicine "Hydroxyacetic Acid" in TOXNET Hazardous Substances Data Bank (HSDB), citing Gerhartz, W. (exec ed.), Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA13 509.
- ^ "DuPont Glycolic Acid Technical Information". Archived from the original on 2006-07-14. Retrieved 2006-07-06.
- ^ "Glycolic acid". www.chemsrc.com. Archived from the original on 2020-07-27. Retrieved 2018-05-16.
- ^ "Glycolic Acid MSDS". University of Akron. Retrieved 2006-09-18.