Ibogainalog

Ibogainalog
Clinical data
Other names	IBG; 9-Methoxyibogaminalog; 9-MeO-ibogaminalog
Drug class	Non-selective serotonin receptor modulator; Serotonin 5-HT2A receptor agonist; Serotonergic psychedelic; Hallucinogen; Psychoplastogen
Identifiers
	IUPAC name 9-methoxy-3-methyl-2,4,5,6-tetrahydro-1H-azepino[4,5-b]indole;
CAS Number	802581-10-8;
PubChem CID	370423;
ChemSpider	328813;
ChEMBL	ChEMBL2009371;
Chemical and physical data
Formula	C14H18N2O
Molar mass	230.311 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CN1CCC2=C(CC1)NC3=C2C=C(C=C3)OC;
	InChI InChI=1S/C14H18N2O/c1-16-7-5-11-12-9-10(17-2)3-4-13(12)15-14(11)6-8-16/h3-4,9,15H,5-8H2,1-2H3; Key:RVVJOBLZASPMDJ-UHFFFAOYSA-N;

Ibogainalog (IBG), also known as 9-methoxyibogaminalog, is a non-selective serotonin receptor modulator, serotonergic psychedelic, and psychoplastogen of the ibogalog group related to the iboga alkaloid ibogaine but with a simplified chemical structure.^[1]^[2]^[3]

^ Zięba A, Stępnicki P, Matosiuk D, Kaczor AA (December 2021). "Overcoming Depression with 5-HT_2A Receptor Ligands". International Journal of Molecular Sciences. 23 (1): 10. doi:10.3390/ijms23010010. PMC 8744644. PMID 35008436.
^ Duan W, Cao D, Wang S, Cheng J (January 2024). "Serotonin 2A Receptor (5-HT_2AR) Agonists: Psychedelics and Non-Hallucinogenic Analogues as Emerging Antidepressants". Chemical Reviews. 124 (1): 124–163. doi:10.1021/acs.chemrev.3c00375. PMID 38033123.
^ Cameron LP, Tombari RJ, Lu J, Pell AJ, Hurley ZQ, Ehinger Y, et al. (January 2021). "A non-hallucinogenic psychedelic analogue with therapeutic potential". Nature. 589 (7842): 474–479. Bibcode:2021Natur.589..474C. doi:10.1038/s41586-020-3008-z. PMC 7874389. PMID 33299186.