Type II cytokine receptor
| Type II cytokine receptor | |
|---|---|
| Identifiers | |
| Symbol | Type II cytokine receptor |
| Pfam clan | CL0159 |
| Membranome | 2 |
| Interferon gamma receptor | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | IFNGR1 | ||||||||
| Pfam | PF07140 | ||||||||
| InterPro | IPR021126 | ||||||||
| SCOP2 | 1fg9 / SCOPe / SUPFAM | ||||||||
| |||||||||
| Interferon-alpha/beta receptor, fibronectin type III | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Interfer-bind | ||||||||
| Pfam | Interfer-bind | ||||||||
| InterPro | IPR015373 | ||||||||
| SCOP2 | 1n6u / SCOPe / SUPFAM | ||||||||
| |||||||||
Type II cytokine receptors, also commonly known as class II cytokine receptors, are transmembrane proteins that are expressed on the surface of certain cells. They bind and respond to a select group of cytokines including interferon type I, interferon type II, interferon type III.[1] and members of the interleukin-10 family[2][3] These receptors are characterized by the lack of a WSXWS motif which differentiates them from type I cytokine receptors.[4]
- ^ Krey K, Babnis AW, Pichlmair A (October 2020). "System-Based Approaches to Delineate the Antiviral Innate Immune Landscape". Viruses. 12 (10): 1196. doi:10.3390/v12101196. PMC 7589202. PMID 33096788.
- ^ Cite error: The named reference
pmid11481447was invoked but never defined (see the help page). - ^ Cite error: The named reference
pmid12521379was invoked but never defined (see the help page). - ^ Stanifer ML, Pervolaraki K, Boulant S (March 2019). "Differential Regulation of Type I and Type III Interferon Signaling". International Journal of Molecular Sciences. 20 (6): 1445. doi:10.3390/ijms20061445. PMC 6471306. PMID 30901970.