Löfgren syndrome

Löfgren syndrome
Löfgren syndrome includes some of the same symptoms as traditional sarcoidosis, and presents with erythema nodosum (especially of the lower extremities), bilateral arthritis of the ankle joints, and hilar lymphadenopathy. (Note: Other symptoms are classically not present in Löfgren syndrome.)

Löfgren syndrome is a type of acute sarcoidosis,[1] an inflammatory disorder characterized by swollen lymph nodes in the chest, tender red nodules on the shins, fever and arthritis.[2] It is more common in women than men, and is more frequent in those of Scandinavian, Irish, African and Puerto Rican heritage. It was described in 1953[3] by Sven Halvar Löfgren, a Swedish clinician.[4] Some have considered the condition to be imprecisely defined.[5]

  1. ^ Ohta H, Tazawa R, Nakamura A, et al. (2006). "Acute-onset sarcoidosis with erythema nodosum and polyarthralgia (Lofgren's syndrome) in Japan: a case report and a review of the literature". Intern. Med. 45 (9): 659–662. doi:10.2169/internalmedicine.45.1452. PMID 16755100.
  2. ^ Cite error: The named reference SamTeo2010 was invoked but never defined (see the help page).
  3. ^ Löfgren S (1953). "Primary pulmonary sarcoidosis. I. Early signs and symptoms". Acta Med Scand. 145 (6): 424–431. doi:10.1111/j.0954-6820.1953.tb07039.x. PMID 13079656.
  4. ^ Sven Halvar Löfgren biography
  5. ^ Grunewald J, Eklund A (January 2007). "Sex-specific manifestations of Löfgren's syndrome". Am. J. Respir. Crit. Care Med. 175 (1): 40–44. doi:10.1164/rccm.200608-1197OC. PMC 1899259. PMID 17023727.
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