Lachnospiraceae

Lachnospiraceae
Scientific classification
Domain: Bacteria
Kingdom: Bacillati
Phylum: Bacillota
Class: Clostridia
Order: Lachnospirales
Family:
Rainey 2010[1]
Genera[2]

See text

The Lachnospiraceae are a family of obligately anaerobic, variably spore-forming bacteria in the order Eubacteriales that ferment diverse plant polysaccharides[3] to short-chain fatty acids (butyrate, acetate) and alcohols (ethanol). These bacteria are among the most abundant taxa in the rumen[4] and the human gut microbiota.[5][6][7][8] Members of this family may protect against colon cancer in humans by producing butyric acid.[9][10] Lachnospiraceae have been found to contribute to diabetes in genetically susceptible (ob/ob) germ-free mice.[11]

  1. ^ Cite error: The named reference LPSN was invoked but never defined (see the help page).
  2. ^ "Family - L". List of Prokaryotic Names with Standing in Nomenclature. Retrieved 30 March 2021.
  3. ^ Boutard, M; Cerisy, T (13 November 2014). "Functional Diversity of Carbohydrate-Active Enzymes Enabling a Bacterium to Ferment Plant Biomass". PLOS Genetics. 10 (11): e1004773. doi:10.1371/journal.pgen.1004773. PMC 4230839. PMID 25393313.
  4. ^ Seshadri, R; Leahy, SC (19 March 2018). "Cultivation and sequencing of rumen microbiome members from the Hungate1000 Collection". Nature Biotechnology. 36 (4): 359–367. doi:10.1038/nbt.4110. PMC 6118326. PMID 29553575.
  5. ^ Cite error: The named reference eol was invoked but never defined (see the help page).
  6. ^ Phyllis Kanki; Darrell Jay Grimes, eds. (2013). Infectious diseases selected entries from the Encyclopedia of sustainability science and technology. New York: Springer. ISBN 978-1-4614-5719-0.
  7. ^ UniProt
  8. ^ Paul De Vos; et al., eds. (2009). Bergey's manual of systematic bacteriology (2nd ed.). Dordrecht: Springer. ISBN 978-0-387-68489-5.
  9. ^ Meehan, C. J.; Beiko, R. G. (12 March 2014). "A Phylogenomic View of Ecological Specialization in the Lachnospiraceae, a Family of Digestive Tract-Associated Bacteria". Genome Biology and Evolution. 6 (3): 703–713. doi:10.1093/gbe/evu050. PMC 3971600. PMID 24625961.
  10. ^ Xia, Li C.; Liu, Gang; Gao, Yingxin; Li, Xiaoxin; Pan, Hongfei; Ai, Dongmei (2019). "Identifying Gut Microbiota Associated With Colorectal Cancer Using a Zero-Inflated Lognormal Model". Frontiers in Microbiology. 10: 826. doi:10.3389/fmicb.2019.00826. ISSN 1664-302X. PMC 6491826. PMID 31068913.
  11. ^ Kameyama, Keishi; Itoh, Kikuji (2014). "Intestinal Colonization by a Lachnospiraceae Bacterium Contributes to the Development of Diabetes in Obese Mice". Microbes and Environments. 29 (4): 427–430. doi:10.1264/jsme2.ME14054. ISSN 1342-6311. PMC 4262368. PMID 25283478.
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