Lactate dehydrogenase elevating virus
| Gammaarterivirus lacdeh | |
|---|---|
| Virus classification | |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Pisuviricota |
| Class: | Pisoniviricetes |
| Order: | Nidovirales |
| Family: | Arteriviridae |
| Genus: | |
| Species: | Gammaarterivirus lacdeh
|
| Synonyms | |
| |
Lactate dehydrogenase elevating virus (LDV) constitutes the species Gamamaarterivirus lacdeh which is part of the family Arteriviridae and order Nidovirales.[1] The order Nidovirales also includes the family of coronaviruses. Arteriviruses infect macrophages in animals and cause a variety of diseases.[2] LDV specifically causes lifelong persistent viremia in mice, but does not harm the host and only slightly harms the immune system. The main clinical sign is an increased level of the plasma enzyme lactate dehydrogenase (LDH). LDV has a remarkably narrow cell type specificity, meaning nothing homologous with LDV in mice has been found in another species.[3]
- ^ "Taxonomy browser (Variarterivirinae)". www.ncbi.nlm.nih.gov. Retrieved 2021-06-17.
- ^ Rowson, K.E.K.; B.W.J. Mahy (1985). "Lactate Dehydrogenase-Elevating Virus". Journal of General Virology. 66 ( Pt 11) (11): 2297–2312. doi:10.1099/0022-1317-66-11-2297. PMID 3903045. Archived from the original on 2008-08-21. Retrieved 2011-05-06.
- ^ Mohammadi, Hakimeh; Shayan Sharif; Raymond R. Rowland; Dongwan Yon (11 June 2009). "The Lactate Dehydrogenase-Elevating Virus Capsid Protein is a Nuclear-Cytoplasmic Protein". Archives of Virology. 154 (7): 1071–1080. doi:10.1007/s00705-009-0410-0. PMC 7087266. PMID 19517211.