Landau–Kleffner syndrome

Landau–Kleffner syndrome
Other namesInfantile acquired aphasia, acquired epileptic aphasia, aphasia with convulsive disorder
Landau–Kleffner syndrome is characterized by aphasia and an abnormal EEG
SpecialtyNeurology, psychiatry 
SymptomsAphasia, inattention, hyperactivity, aggression, anxiety, seizures
Usual onsetAges 3 to 7
DurationLifelong
TreatmentSpeech therapy, medication
MedicationAnticonvulsants, corticosteroids
PrognosisVariable

Landau–Kleffner syndrome (LKS), also called infantile acquired aphasia, acquired epileptic aphasia,[1] or aphasia with convulsive disorder, is a rare neurological syndrome that develops during childhood.[2]

It is named after William Landau and Frank Kleffner, who characterized it in 1957 with a diagnosis of six children.[3][4]

  1. ^ "Landau–Kleffner syndrome" at Dorland's Medical Dictionary
  2. ^ "Landau Kleffner Syndrome - Symptoms, Causes, Treatment | NORD". rarediseases.org. Retrieved 21 April 2024.
  3. ^ Landau WM, Kleffner FR (August 1957). "Syndrome of acquired aphasia with convulsive disorder in children". Neurology. 7 (8): 523–30. doi:10.1212/wnl.7.8.523. PMID 13451887. S2CID 2093377. Reproduced as Landau WM, Kleffner FR (November 1998). "Syndrome of acquired aphasia with convulsive disorder in children. 1957". Neurology. 51 (5): 1241, 8 pages following 1241. doi:10.1212/wnl.51.5.1241-a. PMID 9867583. S2CID 45332481.
  4. ^ "Landau-Kleffner Syndrome (LKS or Infantile Acquired Aphasia)" (medicinenet). Medscape part of WebMD Health Professional Network.