Lhermitte–Duclos disease
| Lhermitte-Duclos disease (LDD) | |
|---|---|
| Other names | Dysplastic gangliocytoma of the cerebellum (DGC) |
| Lhermitte-Duclos disease histology | |
| Specialty | Neuro-oncology |
Lhermitte–Duclos disease (LDD) (English: /ˌlɛərˈmiːtˌduːˈkloʊ/), also called dysplastic gangliocytoma of the cerebellum (DGC), is a rare, slowly growing tumor of the cerebellum, a gangliocytoma sometimes considered to be a hamartoma, characterized by diffuse hypertrophy of the granular layer of the cerebellum. It is often associated with Cowden syndrome.[1] It was described by Jacques Jean Lhermitte and P. Duclos in 1920.[2]
- ^ Eng C (November 2000). "Will the real Cowden syndrome please stand up: revised diagnostic criteria". Journal of Medical Genetics. 37 (11): 828–830. doi:10.1136/jmg.37.11.828. PMC 1734465. PMID 11073535.
- ^ Lhermitte J, Duclos P (1920). "Sur un ganglioneurome diffuse du cortex du cervelet". Bulletin de l'Association Française pour l'Étude du Cancer. 9. Paris: 99–107.