Lipotoxicity

Lipotoxicity is a metabolic syndrome that results from the accumulation of lipid intermediates in non-adipose tissue, leading to cellular dysfunction and death. The tissues normally affected include the kidneys, liver, heart and skeletal muscle. Lipotoxicity is believed to have a role in heart failure, obesity, and diabetes, and is estimated to affect approximately 25% of the adult American population.[1]

  1. ^ Garbarino, Jeanne; Stephen L. Sturley (2009). "Saturated with fat: new perspectives on lipotoxicity". Current Opinion in Clinical Nutrition and Metabolic Care. 12 (2): 110–116. doi:10.1097/mco.0b013e32832182ee. PMID 19202381. S2CID 7169311.
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