Liver failure
| Liver failure | |
|---|---|
| Other names | Hepatic insufficiency, liver dysfunction |
| A person with massive ascites and caput medusae due to cirrhotic liver failure | |
| Specialty | Gastroenterology, hepatology |
| Symptoms | abdominal inflammation, fluid retention, hyperglycemia, nausea, vomiting, jaundice, acute or chronic fatigue, hyponatremia, hypokalemia, respiratory alkalosis, metabolic acidosis, bilirubinuria, glycosuria, pruritus |
| Risk factors | Excessive consumption of alcohol, fatty foods; obesity; Type 2 Diabetes; sharing or reusing syringes |
Liver failure is the inability of the liver to perform its normal synthetic and metabolic functions as part of normal physiology. Two forms are recognised, acute and chronic (cirrhosis).[1] Recently, a third form of liver failure known as acute-on-chronic liver failure (ACLF) is increasingly being recognized.[2]
- ^ O'Grady JG, Schalm SW, Williams R (1993). "Acute liver failure: redefining the syndromes". Lancet. 342 (8866): 273–5. doi:10.1016/0140-6736(93)91818-7. PMID 8101303. S2CID 21583699.
- ^ Arroyo, Vicente; Kamath, Patrick; Moreau, Richard; Jalan, Rajiv (2016). "Acute-on-Chronic Liver Failure: A Distinct Clinical Condition". Seminars in Liver Disease. 36 (2): 107–108. doi:10.1055/s-0036-1583287. PMID 27172350.