MMRV vaccine

MMRV vaccine
Combination of
Measles vaccineVaccine
Mumps vaccineVaccine
Rubella vaccineVaccine
Varicella vaccineVaccine
Clinical data
Trade namesProquad, Priorix Tetra
Other namesMeasles, Mumps, Rubella, and Varicella Virus Vaccine Live
AHFS/Drugs.comMonograph
License data
Pregnancy
category
Routes of
administration		Subcutaneous, intramuscular
ATC code
Legal status
Legal status
Identifiers
CAS Number
ChemSpider
  • none
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The MMRV vaccine is a combination vaccine against measles, mumps, rubella (German measles), and varicella (chickenpox), abbreviated as MMRV. The MMRV vaccine has similar immunogenicity and overall safety profiles to the MMR vaccine administered with or without the varicella vaccine. The MMRV vaccine is typically given to children between one and two years of age.[8]

Several companies supply MMRV vaccines. Proquad is marketed by Merck and was approved in 2005, for use in the United States by the Food and Drug Administration (FDA) for children ages twelve months through twelve years. Stand-alone virus measles, mumps, rubella, and varicella vaccines had been previously licensed in 1963, 1967, 1969, and 1995, respectively.[9][10] An MMRV vaccine called Priorix Tetra[11][12] by GlaxoSmithKline has been approved in Germany and Australia.[13][14][15]

  1. ^ "Measles virus vaccine/mumps virus vaccine/rubella virus vaccine/varicella virus vaccine (Proquad) Use During Pregnancy". Drugs.com. 16 October 2019. Archived from the original on 19 October 2019. Retrieved 26 January 2020.
  2. ^ Cite error: The named reference Proquad AU was invoked but never defined (see the help page).
  3. ^ Cite error: The named reference Priorix-Tetra AU was invoked but never defined (see the help page).
  4. ^ "Proquad Product information". Health Canada. 9 May 2014. Archived from the original on 10 June 2024. Retrieved 10 June 2024.
  5. ^ "Priorix Tetra Product information". Health Canada. 4 June 2008. Archived from the original on 10 June 2024. Retrieved 10 June 2024.
  6. ^ "DailyMed - Proquad- measles, mumps, rubella and varicella virus vaccine live injection, powder, lyophilized, for suspension". Archived from the original on 6 April 2020. Retrieved 9 October 2020.
  7. ^ Cite error: The named reference Proquad EPAR was invoked but never defined (see the help page).
  8. ^ Kowalzik F, Faber J, Knuf M (August 2018). "MMR and MMRV vaccines". Vaccine. Progress in Vaccines. 36 (36): 5402–5407. doi:10.1016/j.vaccine.2017.07.051. PMID 28757060.
  9. ^ Goodson JL, Seward JF (December 2015). "Measles 50 Years After Use of Measles Vaccine". Infectious Disease Clinics of North America. 29 (4): 725–743. doi:10.1016/j.idc.2015.08.001. PMID 26610423.
  10. ^ "Measles: information about the disease and vaccines Questions and Answers" (PDF). Immunization Action Coalition. November 2018. Archived (PDF) from the original on 28 November 2022. Retrieved 28 November 2022.
  11. ^ Wellington K, Goa KL (2003). "Measles, mumps, rubella vaccine (Priorix; GSK-MMR): a review of its use in the prevention of measles, mumps and rubella". Drugs. 63 (19): 2107–2126. doi:10.2165/00003495-200363190-00012. PMID 12962524. S2CID 46973762.
  12. ^ "GlaxoSmithKline Clinical Trial Register". GlaxoSmithKline. Archived from the original on 30 November 2007. Retrieved 19 October 2019.
  13. ^ "Priorix-tetra". The Australian Immunisation Handbook. 4 June 2018. Archived from the original on 19 October 2019. Retrieved 18 October 2019.
  14. ^ Bauchau V, Van Holle L, Cohen C (November 2015). "Modelling Hospitalisation Ratios for Febrile Convulsions and Severe Varicella Under Combined Measles, Mumps, Rubella, and Varicella (MMRV-Priorix-Tetra) Compared to Separate MMR + V Vaccination". Drug Safety. 38 (11): 1095–1102. doi:10.1007/s40264-015-0326-4. PMC 4608986. PMID 26251259.
  15. ^ "PEI Table of vaccines for measles with a valid marketing authorisation". PEI, Paul-Ehrlich-Institut, Bundesinstitut für Impfstoffe und biomedizinische Arzneimittel (in German). 19 October 2019. Archived from the original on 19 October 2019. Retrieved 18 October 2019.
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