Marginal zone
| Marginal zone | |
|---|---|
| Identifiers | |
| FMA | 15852 |
| Anatomical terminology | |
The marginal zone is the region at the interface between the non-lymphoid red pulp and the lymphoid white-pulp of the spleen. (Some sources consider it to be the part of red pulp which borders on the white pulp, while other sources consider it to be neither red pulp nor white pulp.)
A marginal zone also exists in the lymphoid follicles of lymph nodes.[1][2] Those marginal zones contain naive B cells and memory B cells.[1] In contrast to the marginal zone of the spleen, they are not characterized by containing additional non-recirculating B2 cells.[3]
- ^ a b Sangle, Nikhil; Pernick, Nat (2 December 2024) [Originally published 1 November 2013]. "Lymph nodes & spleen, nonlymphoma: Anatomy & histology-lymph nodes". Pathology Outlines. Retrieved 1 February 2025.
- ^ Kojima, Masaru; Nakamura, Shigeo; Motoori, Tadashi; Shimizu, Kazuhiko; Ohno, Yoshihiro; Itoh, Hideakki; Masawa, Nobuhide (2002). "Follicular hyperplasia presenting with a marginal zone pattern in a reactive lymph node lesion". APMIS. 110 (4): 325–331. doi:10.1034/j.1600-0463.2002.100407.x. PMID 12076268.
- ^ Martin, Flavius; Kearney, John F. (May 2002). "Marginal-zone B cells". Nature Reviews Immunology. 2 (5): 323–35. doi:10.1038/nri799. PMID 12033738. S2CID 22573840.