Minimally differentiated acute myeloblastic leukemia

Minimally differentiated acute myeloblastic leukemia
The appearance of acute myeloblastic leukemia, M0 under microscope. Blasts show no Auer rods.
SpecialtyHematology, oncology

Minimally differentiated acute myeloblastic leukemia is a subtype of AML. It is classified as M0 by FAB. It represents 2–3% of all cases of AML.[1] Although minimally differentiated AML was recognized earlier, criteria for FAB M0 were developed in 1987.[2] The blasts in these cases cannot be recognized as myeloid based on morphology and cytochemistry, but immunophenotyping demonstrates myeloid antigens.[3]

  1. ^ Kumar V, Abbas AK, Fausto N, Mitchel RN (2007). Robbins basic Pathology (8th ed.). Saunders.
  2. ^ Lee EJ, Pollak A, Leavitt RD, Testa JR, Schiffer CA (November 1987). "Minimally differentiated acute nonlymphocytic leukemia: a distinct entity". Blood. 70 (5): 1400–6. doi:10.1182/blood.v70.5.1400.bloodjournal7051400. PMID 3663939.
  3. ^ Greer JP, Foerster J, Lukens JN (2003). Wintrobe's Clinical Hematology (11th ed.). Lippincott Williams & Wilkins.
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