Minoxidil

Minoxidil
Clinical data
Trade namesLoniten, Rogaine, others
Other names2,4-Diamino-6-piperidinopyrimidine 3-oxide
AHFS/Drugs.comMonograph
MedlinePlusa682608
License data
Pregnancy
category
Routes of
administration		By mouth, topical
ATC code
Legal status
Legal status
Pharmacokinetic data
Bioavailability>90%
MetabolismPrimarily liver
Elimination half-life4.2 h
ExcretionKidney
Identifiers
IUPAC name
  • 2,6-diamino-4-(piperidin-1-yl)pyrimidine 1-oxide
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
PDB ligand
CompTox Dashboard (EPA)
ECHA InfoCard100.048.959
Chemical and physical data
FormulaC9H15N5O
Molar mass209.253 g·mol−1
3D model (JSmol)
Melting point248 °C (478 °F)
Solubility in water<1
SMILES
  • Nc1cc(nc(N)[n+]1[O-])N2CCCCC2
InChI
  • InChI=1S/C9H15N5O/c10-7-6-8(12-9(11)14(7)15)13-4-2-1-3-5-13/h6H,1-5,10H2,(H2,11,12) N
  • Key:ZFMITUMMTDLWHR-UHFFFAOYSA-N N
 NY (what is this?)  (verify)

Minoxidil is a medication used for the treatment of high blood pressure and pattern hair loss.[4][5][6] It is an antihypertensive and a vasodilator.[9] It is available as a generic medication by prescription in oral tablet form and over-the-counter as a topical liquid or foam.[7][8][10][11]

  1. ^ a b "Loniten Product Information". Therapeutic Goods Administration (TGA). Archived from the original on August 16, 2021. Retrieved August 15, 2021.
  2. ^ "59445 WOMEN'S REGAINE EXTRA STRENGTH Minoxidil 5% application bottle". Therapeutic Goods Administration (TGA) / Australian Government Department of Health and Aged Care. Retrieved February 15, 2022.
  3. ^ "Search the TGA website". Tga-search.clients.funnelback.com. Archived from the original on August 16, 2021.
  4. ^ a b "Loniten Tablets 5mg - Summary of Product Characteristics (SmPC)". Medicines.org.uk. November 24, 2020. Archived from the original on August 16, 2021. Retrieved August 15, 2021.
  5. ^ a b "Regaine for Men Extra Strength Scalp Foam 5% w/w Cutaneous Foam (GSL) - Summary of Product Characteristics (SmPC)". (emc). April 27, 2021. Archived from the original on August 16, 2021. Retrieved August 15, 2021.
  6. ^ a b "Regaine for Women Once a Day Scalp Foam 5% w/w Cutaneous Foam - Summary of Product Characteristics (SmPC)". Medicines.org.uk. October 28, 2020. Archived from the original on August 16, 2021. Retrieved August 15, 2021.
  7. ^ a b "Minoxidil tablet". DailyMed. Archived from the original on August 16, 2021. Retrieved August 15, 2021.
  8. ^ a b "Minoxidil aerosol, foam". DailyMed. Archived from the original on August 16, 2021. Retrieved August 15, 2021.
  9. ^ "Vasodilators". mayoclinic.com. Archived from the original on March 9, 2011.
  10. ^ "Mens Rogaine Extra Strength Unscented- minoxidil solution". DailyMed. Archived from the original on August 16, 2021. Retrieved August 15, 2021.
  11. ^ "Womens Rogaine Unscented- minoxidil solution". DailyMed. Archived from the original on August 16, 2021. Retrieved August 15, 2021.
This article is issued from Wikipedia. The text is available under Creative Commons Attribution-Share Alike 4.0 unless otherwise noted. Additional terms may apply for the media files.