Mometasone/formoterol
| Combination of | |
|---|---|
| Mometasone furoate | Corticosteroid |
| Formoterol fumarate | Long-acting β2 adrenoreceptor agonist (LABA) |
| Clinical data | |
| Trade names | Zenhale, Dulera, others |
| AHFS/Drugs.com | Professional Drug Facts |
| License data | |
| Routes of administration | Inhalation (Metered-dose inhaler MDI) |
| ATC code | |
| Legal status | |
| Legal status | |
| Identifiers | |
| CAS Number | |
| KEGG | |
| (what is this?) (verify) | |
Mometasone/formoterol, sold under the brand name Dulera among others, is a fixed-dose combination medication used in the long-term treatment of asthma.[1] It contains mometasone a steroid and formoterol a long-acting beta agonist.[1] It is only recommended in those for whom an inhaled steroid is not sufficient.[1] It is used by inhalation.[1]
Common side effect include headache and sinusitis.[1] More serious side effects may include thrush, immunosuppression, allergic reactions, and cataracts.[1] Use is not recommended in those less than twelve years of age.[1] It has not been studied during pregnancy or breastfeeding.[1] Mometasone works by decreasing inflammation while formoterol works by relaxing smooth muscle in the airways.[1]
The combination was approved for medical use in the United States in 2010.[1] No generic version is available as of 2019. In 2021, it was the 215th most commonly prescribed medication in the United States, with more than 1 million prescriptions.[2][3] It is on the World Health Organization's List of Essential Medicines.[4]
- ^ a b c d e f g h i j "Dulera- mometasone furoate and formoterol fumarate dihydrate aerosol". DailyMed. 12 August 2019. Retrieved 29 April 2020.
- ^ "The Top 300 of 2021". ClinCalc. Archived from the original on 15 January 2024. Retrieved 14 January 2024.
- ^ "Formoterol; Mometasone - Drug Usage Statistics". ClinCalc. Retrieved 14 January 2024.
- ^ World Health Organization (2021). World Health Organization model list of essential medicines: 22nd list (2021). Geneva: World Health Organization. hdl:10665/345533. WHO/MHP/HPS/EML/2021.02.