Neonatal encephalopathy

Neonatal encephalopathy
Other namesHypoxic and ischemic brain injury in the newborn, perinatal asphyxia, neonatal hypoxic and ischemic brain injury
SpecialtyPediatrics 

Neonatal encephalopathy (NE), previously known as neonatal hypoxic-ischemic encephalopathy (neonatal HIE or NHIE), is defined as a encephalopathy syndrome with signs and symptoms of abnormal neurological function, in the first few days of life in an infant born after 35 weeks of gestation. [1][2] In this condition there is difficulty initiating and maintaining respirations, a subnormal level of consciousness, and associated depression of tone, reflexes, and possibly seizures.[3] Hypoxia refers to deficiency of oxygen, Ischemia refers to restriction in blood flow to the brain. The result is “encephalopathy” which refers to damaged brain cells. Encephalopathy is a nonspecific response of the brain to injury which may occur via multiple methods, but is commonly caused by birth asphyxia, leading to cerebral hypoxia. [2][3]

  1. ^ Neonatal Encephalopathy and Neurologic Outcome (Second ed.). American Academy of Pediatrics. 2017-04-17. p. 1518. doi:10.1542/9781610020862-part06-neonatal_encephalopathy. ISBN 978-1-934984-30-7. S2CID 243921388.
  2. ^ a b "Neonatal Encephalopathy". adhb.govt.nz. Retrieved 7 March 2015.
  3. ^ a b Perlman JM, Polin RA (2008). Neurology. Philadelphia: Saunders/Elsevier. ISBN 9781416031574. OCLC 489075193.
This article is issued from Wikipedia. The text is available under Creative Commons Attribution-Share Alike 4.0 unless otherwise noted. Additional terms may apply for the media files.