Noribogainalog

Noribogainalog
Clinical data
Other names	Nor-IBG; 9-Hydroxyibogaminalog
Identifiers
	IUPAC name 3-methyl-2,4,5,6-tetrahydro-1H-azepino[4,5-b]indol-9-ol;
CAS Number	411220-25-2;
PubChem CID	154694300;
ChemSpider	74888746;
Chemical and physical data
Formula	C13H16N2O
Molar mass	216.284 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CN1CCC2=C(CC1)NC3=C2C=C(C=C3)O;
	InChI InChI=1S/C13H16N2O/c1-15-6-4-10-11-8-9(16)2-3-12(11)14-13(10)5-7-15/h2-3,8,14,16H,4-7H2,1H3; Key:OOROJSRWMMKEQK-UHFFFAOYSA-N;

Noribogainalog (nor-IBG), also known as 9-hydroxyibogaminalog, is a drug of the ibogalog family related to noribogaine.^[1]^[2] It is a simplified analogue of noribogaine.^[1]^[2]

^ ^a ^b Cameron LP, Tombari RJ, Lu J, Pell AJ, Hurley ZQ, Ehinger Y, et al. (January 2021). "A non-hallucinogenic psychedelic analogue with therapeutic potential". Nature. 589 (7842): 474–479. Bibcode:2021Natur.589..474C. doi:10.1038/s41586-020-3008-z. PMC 7874389. PMID 33299186.
^ ^a ^b Arias HR, Micheli L, Jensen AA, Galant S, Vandermoere F, Venturi D, et al. (March 2025). "Ibogalogs decrease neuropathic pain in mice through a mechanism involving crosstalk between 5-HT2A and mGlu2 receptors". Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 184 117887: 117887. doi:10.1016/j.biopha.2025.117887. hdl:2158/1423286. PMID 39938347.

[Cameron_2021-1] Cameron LP, Tombari RJ, Lu J, Pell AJ, Hurley ZQ, Ehinger Y, et al. (January 2021). "A non-hallucinogenic psychedelic analogue with therapeutic potential". Nature. 589 (7842): 474–479. Bibcode:2021Natur.589..474C. doi:10.1038/s41586-020-3008-z. PMC 7874389. PMID 33299186.

[Arias_2025-2] Arias HR, Micheli L, Jensen AA, Galant S, Vandermoere F, Venturi D, et al. (March 2025). "Ibogalogs decrease neuropathic pain in mice through a mechanism involving crosstalk between 5-HT2A and mGlu2 receptors". Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 184 117887: 117887. doi:10.1016/j.biopha.2025.117887. hdl:2158/1423286. PMID 39938347.

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