Periodic fever, aphthous stomatitis, pharyngitis and adenitis

Periodic fever, aphthous stomatitis, pharyngitis and adenitis
Other namesPeriodic fever aphthous pharyngitis and cervical adenopathy (PFAPA)
SpecialtyPediatric, Rheumatology, Immunology
SymptomsFever recurring on a ~2–6 week cycle
TreatmentTonsillectomy
MedicationCorticosteroids, Colchicine, Cimetidine

Periodic fever, aphthous stomatitis, pharyngitis and adenitis syndrome is a medical condition, typically occurring in young children, in which high fever occurs periodically at intervals of about 3–5 weeks, frequently accompanied by aphthous-like ulcers, pharyngitis and cervical adenitis (cervical lymphadenopathy). The syndrome was described in 1987 and named two years later.[1][2][3]

  1. ^ Thomas KT, Feder HM, Lawton AR, Edwards KM (July 1999). "Periodic fever syndrome in children". The Journal of Pediatrics. 135 (1): 15–21. doi:10.1016/S0022-3476(99)70321-5. PMID 10393598.
  2. ^ Cite error: The named reference padeh_PFAPA was invoked but never defined (see the help page).
  3. ^ Long SS (July 1999). "Syndrome of Periodic Fever, Aphthous stomatitis, Pharyngitis, and Adenitis (PFAPA)--what it isn't. What is it?". The Journal of Pediatrics. 135 (1). Mosby: 1–5. doi:10.1016/S0022-3476(99)70316-1. PMID 10393593.