Pancreatic serous cystadenoma

Pancreatic serous cystadenoma
Other namesSerous cystadenoma of the pancreas, serous microcystic adenoma
Micrograph showing a pancreatic serous cystadenoma. H&E stain.
SpecialtyGeneral surgery, gastroenterology
SymptomsUsually asymptomatic
Usual onset50–60 years of age
Risk factorsFemale gender
TreatmentSurgical resection (if symptomatic)
Deaths0.1%[1]

Pancreatic serous cystadenoma is a benign tumour of the pancreas.[2] It is usually solitary and found in the body or tail of the pancreas, and may be associated with von Hippel–Lindau syndrome.[2]

In contrast to some of the other cyst-forming tumors of the pancreas (such as the intraductal papillary mucinous neoplasm and the pancreatic mucinous cystadenoma), serous cystic neoplasms are almost always entirely benign. There are some exceptions; rare case reports have described isolated malignant serous cystadenocarcinomas.[3] In addition, serous cystic neoplasms slowly grow, and if they grow large enough they can press on adjacent organs and cause symptoms.

  1. ^ Jais B, Rebours V, Malleo G, Salvia R, Fontana M, Maggino L, et al. (February 2016). "Serous cystic neoplasm of the pancreas: a multinational study of 2622 patients under the auspices of the International Association of Pancreatology and European Pancreatic Club (European Study Group on Cystic Tumors of the Pancreas)". Gut. 65 (2): 305–312. doi:10.1136/gutjnl-2015-309638. hdl:11577/3187425. PMID 26045140. S2CID 206962150.
  2. ^ a b WHO Classification of Tumours Editorial Board (2019). "10. Tumours of the pancreas: Pancreatic serous cystadenoma". Digestive System Tumours. Vol. 1 (5th ed.). Lyon (France). pp. 303–306. ISBN 978-92-832-4499-8.{{cite book}}: CS1 maint: location missing publisher (link)
  3. ^ Galanis C, Zamani A, Cameron JL, Campbell KA, Lillemoe KD, Caparrelli D, et al. (July 2007). "Resected serous cystic neoplasms of the pancreas: a review of 158 patients with recommendations for treatment". Journal of Gastrointestinal Surgery. 11 (7): 820–826. doi:10.1007/s11605-007-0157-4. PMID 17440789. S2CID 32023143.