Penpulimab

Penpulimab
Monoclonal antibody
TypeWhole antibody
SourceHumanized (from mouse)
TargetPD-1
Clinical data
Other namesAK105, penpulimab-kcqx
MedlinePlusa625068
License data
Routes of
administration
Intravenous
Drug classAntineoplastic agent
ATC code
  • None
Legal status
Legal status
Identifiers
CAS Number
PubChem SID
IUPHAR/BPS
DrugBank
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC6434H9922N1718O2012S46
Molar mass145008.92 g·mol−1

Penpulimab is a humanized monoclonal antibody used for the treatment of cancer.[1] It targets the programmed cell death protein 1 (PD-1) receptor.[1][2]

Penpulimab was approved for medical use in China in August 2021,[3] and in the United States in April 2025.[4]

  1. ^ a b c "Penpulimab-kcqx- penpulimab injection". DailyMed. 24 April 2025. Retrieved 7 July 2025.
  2. ^ "Penpulimab - Akeso Biopharma/Chia Tai Tianqing Pharmaceutical Group". AdisInsight. Springer Nature Switzerland AG.
  3. ^ Cite error: The named reference Dhillon_2021 was invoked but never defined (see the help page).
  4. ^ "FDA approves penpulimab-kcqx for non-keratinizing nasopharyngeal carcinoma". U.S. Food and Drug Administration (FDA). 23 April 2025. Archived from the original on 24 April 2025. Retrieved 24 April 2025. This article incorporates text from this source, which is in the public domain.