Perls Prussian blue

In histology, histopathology, and clinical pathology, Perls Prussian blue is a commonly used method to detect the presence of iron in tissue or cell samples.[1]: 235 [2][3][4] Perls Prussian Blue derives its name from the German pathologist Max Perls (1843–1881), who described the technique in 1867.[2] The method does not involve the application of a dye but rather causes the pigment Prussian blue to form directly within the tissue.[5] The method stains mostly iron in the ferric state which includes ferritin and hemosiderin, rather than iron in the ferrous state.[6]

  1. ^ Cite error: The named reference Bancroft and Stevens, 2008 was invoked but never defined (see the help page).
  2. ^ a b Cite error: The named reference Meguro et al., 2007 was invoked but never defined (see the help page).
  3. ^ Cite error: The named reference Parmley et al., 1978 was invoked but never defined (see the help page).
  4. ^ Cite error: The named reference Theil, 2012 was invoked but never defined (see the help page).
  5. ^ Cite error: The named reference Drury and Wallington, 1980 was invoked but never defined (see the help page).
  6. ^ Cite error: The named reference Iezzoni, 2018 was invoked but never defined (see the help page).
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