Pichia kudriavzevii

Pichia kudriavzevii
Pichia kudriavzevii growth on Sabouraud dextrose agar
Scientific classification
Kingdom: Fungi
Division: Ascomycota
Class: Pichiomycetes
Order: Pichiales
Family: Pichiaceae
Genus: Pichia
Species:
P. kudriavzevii
Binomial name
Pichia kudriavzevii
Boidin, Pignal & Besson (1965)
Synonyms
  • Candida brassicae Amano
  • Candida krusei (Castell.) Berkhout (1923)[1][2]

Pichia kudriavzevii (formerly Candida krusei[1][2]) is a budding yeast (a species of fungus) involved in chocolate production. P. kudriavzevii is an emerging fungal nosocomial pathogen[3] primarily found in the immunocompromised and those with hematological malignancies. It has natural resistance to fluconazole, a standard antifungal agent. It is most often found in patients who have had prior fluconazole exposure, sparking debate and conflicting evidence as to whether fluconazole should be used prophylactically. Mortality due to P. kudriavzevii fungemia is much higher than the more common C. albicans. Other Candida species that also fit this profile are C. parapsilosis, C. glabrata, C. tropicalis, C. guillermondii and C. rugosa.

P. kudriavzevii can be successfully treated with voriconazole, amphotericin B, and echinocandins (micafungin, caspofungin, and anidulafungin).

  1. ^ a b Borman AM, Johnson EM (2021). "Name Changes for Fungi of Medical Importance, 2018 to 2019". Journal of Clinical Microbiology. 59 (2). doi:10.1128/JCM.01811-20. PMC 8111128. PMID 33028600.
  2. ^ a b Kidd SE, Abdolrasouli A, Hagen F (2023). "Fungal Nomenclature: Managing Change is the Name of the Game". Open Forum Infectious Diseases. 10 (1): ofac559. doi:10.1093/ofid/ofac559. PMC 9825814. PMID 36632423.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  3. ^ Mastromarino P, Vitali B, Mosca L (July 2013). "Bacterial vaginosis: a review on clinical trials with probiotics" (PDF). The New Microbiologica. 36 (3): 229–238. PMID 23912864.