Pneumonic plague
| Pneumonic plague | |
|---|---|
| A scanning electron micrograph depicting a mass of Yersinia pestis bacteria | |
| Specialty | Infectious disease |
| Symptoms | Fever, headache, shortness of breath, cough, coughing up blood[1] |
| Usual onset | 3 to 7 days[2] |
| Causes | Yersinia pestis[3] |
| Risk factors | Rodents[3] |
| Diagnostic method | Sputum testing[1] |
| Treatment | Antibiotics[1] |
| Prognosis | Nearly 100% fatal if untreated[4] |
| Frequency | 3% of all Plague cases (CDC MMWR 2015) [5] |
Pneumonic plague is a severe lung infection caused by the bacterium Yersinia pestis.[3] Symptoms include fever, headache, shortness of breath, chest pain, coughing, and coughing up blood.[1] They typically start about three to seven days after exposure.[2] It is one of three forms of plague, the other two being septicemic plague and bubonic plague.[3]
The pneumonic form may occur following an initial bubonic or septicemic plague infection.[3] It may also result from breathing in airborne droplets from another person or animal infected with pneumonic plague.[1] The difference between the forms of plague is the location of infection; in pneumonic plague the infection is in the lungs, in bubonic plague the lymph nodes, and in septicemic plague within the blood.[3] Diagnosis is by testing the blood, sputum, or fluid from a lymph node.[1]
While vaccines are being developed, in most countries they are not yet commercially available.[1][3] Prevention is by avoiding contact with infected rodents, people, or cats.[1][3] It is recommended that those infected be isolated from others.[2] Treatment of pneumonic plague consists of antibiotics.[1]
Plague is present among rodents in Africa, the Americas, and Asia.[3] Pneumonic plague is more serious and less common than bubonic plague.[1] The total reported number of cases of all types of plague in 2013 was 783.[2] Left untreated, pneumonic plague is almost always fatal.[6] Some hypothesize that the pneumonic version of the plague was mainly responsible for the Black Death that resulted in approximately 25 million deaths in the 1300s.[2][7]
- ^ a b c d e f g h i j "FAQ Plague". www.cdc.gov. Archived from the original on 14 March 2017. Retrieved 13 March 2017.
- ^ a b c d e "Plague". World Health Organization. September 2016. Archived from the original on 24 April 2015. Retrieved 14 March 2017.
- ^ a b c d e f g h i "Plague". www.who.int. Archived from the original on 19 March 2017. Retrieved 14 March 2017.
- ^ https://web.archive.org/web/20170131062743/http://www.cfsph.iastate.edu/Factsheets/pdfs/plague.pdf
- ^ "Human Plague — United States, 2015". www.cdc.gov. 28 August 2015. Archived from the original on 11 February 2025. Retrieved 14 March 2025.
- ^ http://www.cfsph.iastate.edu/Factsheets/pdfs/plague.pdf
- ^ McCoy, Terrence (31 March 2014). "Everything you know about the Black Death is wrong". Washington Post. The Washington Post. Archived from the original on 27 August 2016. Retrieved 14 March 2017.