Porphyromonas
| Porphyromonas | |
|---|---|
| Colonies of Porphyromonas gulae growing on a TSA plate | |
| Scientific classification | |
| Domain: | Bacteria |
| Kingdom: | Pseudomonadati |
| Phylum: | Bacteroidota |
| Class: | Bacteroidia |
| Order: | Bacteroidales |
| Family: | Porphyromonadaceae |
| Genus: | Shah and Collins 1988[1] |
| Type species | |
| Porphyromonas asaccharolytica[1] | |
| Species | |
|
P. asaccharolytica[1] | |
| Synonyms[2] | |
| |
Porphyromonas is a Gram-negative, non-spore-forming, obligately anaerobic and non-motile genus from the family Porphyromonadaceae.[3][1][2][4] There were 16 different Porphyromonas species documented as of 2015, which reside in both animal and human reservoirs.[5] It was discovered more recently that Porphyromonas also exist in the environment, albeit to a lesser extent.[6] This genus is notably implicated in the modulation of oral cavity, respiratory tract, and gastrointestinal tract disease states.[5] It is suggested that Porphyromonas either operate as benign bacteria pertinent to host immunity or are potential pathobionts that opportunistically provoke diseased states when homeostasis is disrupted.[6] Despite its characterization not being fully elucidated due to sparse research, various studies report the prevalence of this genus at 58.7% in healthy states compared with 41.3% in diseased states.[6]
This genus was first reported in the oral cavity[5] and is found specifically in the salivary microbiome.[7] Porphyromonas are also commonly found in the microbiome of the human digestive tract, as shown by the Human Microbiome Project in general.[8]
- ^ a b c d e f g h i j k l m n o p q r s t Parte, A.C. "Porphyromonas". LPSN.
- ^ a b "Porphyromonas". www.uniprot.org.
- ^ Summanen, Paula; Finegold, Sydney M. (1 January 2015). "Porphyromonas". Bergey's Manual of Systematics of Archaea and Bacteria. John Wiley & Sons, Ltd. pp. 1–14. doi:10.1002/9781118960608.gbm00246. ISBN 9781118960608.
- ^ Parker, Charles Thomas; Wigley, Sarah; Garrity, George M (2009). Parker, Charles Thomas; Garrity, George M (eds.). "Nomenclature Abstract for Porphyromonas". The NamesforLife Abstracts. doi:10.1601/nm.8020.
- ^ a b c Guilloux, Charles-Antoine; Lamoureux, Claudie; Beauruelle, Clémence; Héry-Arnaud, Geneviève (April 2021). "Porphyromonas: A neglected potential key genus in human microbiomes". Anaerobe. 68 102230. doi:10.1016/j.anaerobe.2020.102230. ISSN 1075-9964. PMID 32615270. S2CID 220329292.
- ^ a b c Acuña-Amador, Luis; Barloy-Hubler, Frédérique (December 2020). "Porphyromonas spp. have an extensive host range in ill and healthy individuals and an unexpected environmental distribution: A systematic review and meta-analysis". Anaerobe. 66 102280. doi:10.1016/j.anaerobe.2020.102280. hdl:10669/81718. ISSN 1075-9964. PMID 33011277. S2CID 222169436.
- ^ Wang, Kun; Lu, Wenxin; Tu, Qichao; Ge, Yichen; He, Jinzhi; Zhou, Yu; Gou, Yaping; Nostrand, Joy D Van; Qin, Yujia; Li, Jiyao; Zhou, Jizhong; Li, Yan; Xiao, Liying; Zhou, Xuedong (10 March 2016). "Preliminary analysis of salivary microbiome and their potential roles in oral lichen planus". Scientific Reports. 6 (1): 22943. Bibcode:2016NatSR...622943W. doi:10.1038/srep22943. PMC 4785528. PMID 26961389.
- ^ The Human Microbiome Project Consortium (June 2012). "Structure, function and diversity of the healthy human microbiome". Nature. 486 (7402): 207–214. Bibcode:2012Natur.486..207T. doi:10.1038/nature11234. ISSN 0028-0836. PMC 3564958. PMID 22699609.