Orthostatic albuminuria
| Orthostatic albuminuria | |
|---|---|
| Other names | Orthostatic proteinuria, Postural proteinuria, Postural albuminuria. |
| The structure of Human serum albumin (HSA) complexed with 6 palmitic acid molecules | |
| Pronunciation | |
| Specialty | Urology |
| Usual onset | Under 30 years old[3] |
| Diagnostic method | Urine test strip, Urine protein/creatinine ratio, 24 hour urine collection, renal function tests, and urine microscopy.[3] |
| Differential diagnosis | Transient proteinuria[4] |
| Prognosis | Benign.[3] |
| Frequency | 3 to 5% of adults and teenagers[3] |
Orthostatic albuminuria, also known as orthostatic proteinuria is defined by raised levels of urine protein excretion while in an upright position. In orthostatic albuminuria urine protein excretion returns to normal while in a supine position, such as laying down. Orthostatic albuminuria is the most common cause of isolated proteinuria in those under 20.[5] The prevalence of orthostatic albuminuria is suspected to be between 2 and 5%,[6] however some studies suggest that it is more common.[7] Orthostatic albuminuria is diagnosed if urine protein levels are normal in a morning urine sample and there are no other obvious causes of albuminuria.[8] Patients with orthostatic albuminuria are often asymptomatic and there is no indication for any type of treatment or interventions.[4]
- ^ "Definition of Orthostatic". Merriam-Webster. November 10, 2023. Retrieved November 24, 2023.
- ^ "albuminuria". Oxford English Dictionary. Oxford University Press. July 2023. Retrieved 24 November 2023.
- ^ a b c d Moses, Scott (February 17, 2017). "Orthostatic Proteinuria". Family Practice Notebook. Retrieved November 24, 2023.
- ^ a b "UpToDate". UpToDate. Retrieved November 24, 2023.
- ^ Uehara, K.; Tominaga, N.; Shibagaki, Y. (May 25, 2014). "Adult orthostatic proteinuria". Clinical Kidney Journal. 7 (3): 327–328. doi:10.1093/ckj/sfu040. ISSN 2048-8505. PMC 4377758. PMID 25852903.
- ^ Mazzoni, M. B. M.; Kottanatu, L.; Simonetti, G. D.; Ragazzi, M.; Bianchetti, M. G.; Fossali, E. F.; Milani, G. P. (July 23, 2010). "Renal vein obstruction and orthostatic proteinuria: a review". Nephrology Dialysis Transplantation. 26 (2): 562–565. doi:10.1093/ndt/gfq444. ISSN 0931-0509. PMID 20656752. Retrieved November 24, 2023.
- ^ Vehaskari, V. Matti; Rapola, Juhani (1982). "Isolated proteinuria: Analysis of a school-age population". The Journal of Pediatrics. 101 (5): 661–668. doi:10.1016/s0022-3476(82)80287-4. ISSN 0022-3476. PMID 7131137.
- ^ AK, Leung; AH, Wong; SS, Barg (2017). "Proteinuria in Children: Evaluation and Differential Diagnosis". American Family Physician. 95 (4): 248–254. ISSN 1532-0650. PMID 28290633. Retrieved November 24, 2023.