Primary mediastinal B-cell lymphoma

Primary mediastinal large B-cell lymphoma
Micrograph of a primary mediastinal large B-cell lymphoma. H&E stain.
SpecialtyHematology and oncology

Primary mediastinal B-cell lymphoma, abbreviated PMBL or PMBCL, is a rare type of lymphoma that forms in the mediastinum (the space in between the lungs) and predominantly affects young adults.[1][2][3]

While it had previously been considered a subtype of diffuse large B-cell lymphoma;,[4] the World Health Organization no longer classifies it as such, based on distinct clinicopathologic and molecular features.[5]

  1. ^ Johnson PW, Davies AJ (2008). "Primary mediastinal B-cell lymphoma". Hematology. American Society of Hematology. Education Program. 2008: 349–58. doi:10.1182/asheducation-2008.1.349. PMID 19074109.
  2. ^ Coso D, Rey J, Bouabdallah R (February 2010). "[Primary mediastinal B-cell lymphoma]". Revue de Pneumologie Clinique. 66 (1): 32–5. doi:10.1016/j.pneumo.2009.12.007. PMID 20207294.
  3. ^ Cite error: The named reference Yu2021 was invoked but never defined (see the help page).
  4. ^ "Types of Non-Hodgkin Lymphoma". www.cancer.org. Retrieved 2017-09-28.
  5. ^ "Primary mediastinal large B-cell lymphoma". ashpublications.org/blood/article/140/9/955/476814/Primary-mediastinal-large-B-cell-lymphoma.
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