Prorenin

Prorenin (/prəˈriːnɪn/[1]) is a protein that constitutes a precursor for renin,[2] the hormone that activates the renin–angiotensin system, which serves to raise blood pressure. Prorenin is converted into renin by the juxtaglomerular cells, which are specialised smooth muscle cells present mainly in the afferent, but also the efferent, arterioles of the glomerular capillary bed.

Prorenin is a relatively large molecule, weighing approximately 46 KDa.[3]

  1. ^ "Renin | Definition of Renin by Lexico". Lexico Dictionaries | English. Archived from the original on November 9, 2019.
  2. ^ Jan Danser, A.H. (May 2006). "Prorenin: Back Into the Arena". Hypertension. 47 (5): 824–826. doi:10.1161/01.HYP.0000215952.91959.4a. PMID 16585418.
  3. ^ Cite error: The named reference pringle was invoked but never defined (see the help page).
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