Pseudorabies
| Pseudorabies virus | |
|---|---|
| Virus classification | |
| (unranked): | Virus |
| Realm: | Duplodnaviria |
| Kingdom: | Heunggongvirae |
| Phylum: | Peploviricota |
| Class: | Herviviricetes |
| Order: | Herpesvirales |
| Family: | Orthoherpesviridae |
| Genus: | Varicellovirus |
| Species: | Varicellovirus suidalpha1
|
| Synonyms[1] | |
| |
Aujeszky's disease, usually called pseudorabies in the United States, is a viral disease in swine that is endemic in most parts of the world. It is caused by pseudorabies virus (PRV). Aujeszky's disease is considered to be the most economically important viral disease of swine in areas where classical swine fever (hog cholera) has been eradicated.[2] Other mammals, such as cattle, sheep, goats, cats, dogs, and raccoons, are also susceptible. The disease is usually fatal in these animal species.
Research on PRV in pigs has pioneered animal disease control with genetically modified vaccines. PRV is now used in model studies of basic processes during lytic herpesvirus infection, and for unravelling molecular mechanisms of herpesvirus neurotropism.[3][4]
- ^ "History of the taxon: Species: Varicellovirus suidalpha1 (2023 Release, MSL #39)". ictv.global. International Committee on Taxonomy of Viruses. Retrieved 29 January 2025.
- ^ Fenner, Frank J.; Gibbs, E. Paul J.; Murphy, Frederick A.; Rott, Rudolph; Studdert, Michael J.; White, David O. (1993). Veterinary Virology (2nd ed.). Academic Press, Inc. ISBN 978-0-12-253056-2.
- ^ Mettenleiter (2008). "Molecular Biology of Animal Herpesviruses". Animal Viruses: Molecular Biology. Caister Academic Press. ISBN 978-1-904455-22-6.
- ^ Sandri-Goldin, RM, ed. (2006). Alpha Herpesviruses: Molecular and Cellular Biology. Caister Academic Press. ISBN 978-1-904455-09-7.