Pyramidal signs

Pyramidal signs indicate that the pyramidal tract is affected at some point in its course. Pyramidal tract dysfunction can lead to various clinical presentations such as spasticity, weakness, slowing of rapid alternating movements, hyperreflexia, and a positive Babinski sign.[1]

The pyramidal tract completes development and myelinization between 2 and 3 years of age.[2] Pyramidal signs occur as a normal phenomena until the age of 2, when the myelinization is finished, and so under this age they aren't considered pathological.

  1. ^ Grant, Gerald A.; Xu, Linda; Ellenbogen, Richard G. (2018). "3 - Clinical Evaluation of the Nervous System". Principles of Neurological Surgery (Fourth ed.). doi:10.1016/B978-0-323-43140-8.00003-2. ISBN 978-0-323-43140-8.
  2. ^ Lohia, Akash; McKenzie, Juanette (2024), "Neuroanatomy, Pyramidal Tract Lesions", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID 31082020, retrieved 2024-02-16
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