Satellite glial cell
| Satellite glial cell | |
|---|---|
Satellite glial cells surround the cell bodies of sensory neurons | |
| Details | |
| Location | Surface of neuron bodies in sensory, sympathetic and parasympathetic ganglia |
| Identifiers | |
| Latin | gliocytus ganglionicus |
| MeSH | D027161 |
| NeuroLex ID | sao792373294 |
| TH | H2.00.06.2.02002 |
| Anatomical terms of microanatomy | |
Satellite glial cells, formerly called amphicytes,[1] are glial cells that cover the surface of neuron cell bodies in ganglia of the peripheral nervous system. Thus, they are found in sensory, sympathetic, and parasympathetic ganglia.[2][3] Both satellite glial cells (SGCs) and Schwann cells (the cells that ensheathe some nerve fibers in the PNS) are derived from the neural crest of the embryo during development.[4] SGCs have been found to play a variety of roles, including control over the microenvironment of sympathetic ganglia.[3] They are thought to have a similar role to astrocytes in the central nervous system (CNS).[3] They supply nutrients to the surrounding neurons and also have some structural function. Satellite cells also act as protective, cushioning cells. Additionally, they express a variety of receptors that allow for a range of interactions with neuroactive chemicals.[5] Many of these receptors and other ion channels have recently been implicated in health issues including chronic pain[6] and herpes simplex.[7] There is much more to be learned about these cells, and research surrounding additional properties and roles of the SGCs is ongoing.[8]
- ^ Krstić, Radivoj V. (1985). "Glia of the Central Nervous System. Ependymal Cells". General Histology of the Mammal. Springer. pp. 302–303. doi:10.1007/978-3-642-70420-8_147. ISBN 978-3-642-70420-8.
- ^ Hanani M (June 2005). "Satellite glial cells in sensory ganglia: from form to function" (PDF). Brain Res. Brain Res. Rev. 48 (3): 457–76. doi:10.1016/j.brainresrev.2004.09.001. PMID 15914252. S2CID 5316025.
- ^ a b c Hanani M (September 2010). "Satellite glial cells in sympathetic and parasympathetic ganglia: in search of function". Brain Res Rev. 64 (2): 304–27. doi:10.1016/j.brainresrev.2010.04.009. PMID 20441777. S2CID 11833205.
- ^ Hall AK; Landis SC (September 1992). "Division and migration of satellite glia in the embryonic rat superior cervical ganglion". J. Neurocytol. 21 (9): 635–47. doi:10.1007/bf01191725. PMID 1403009. S2CID 42893326.
- ^ Shinder V; Devor M (September 1994). "Structural basis of neuron-to-neuron cross-excitation in dorsal root ganglia". J. Neurocytol. 23 (9): 515–31. doi:10.1007/bf01262054. PMID 7815085. S2CID 37909973.
- ^ Villa G; Fumagalli M; Verderio C; Abbracchio MP; Ceruti S (February 2010). "Expression and contribution of satellite glial cells purinoceptors to pain transmission in sensory ganglia: an update". Neuron Glia Biol. 6 (1): 31–42. doi:10.1017/S1740925X10000086. PMID 20604978.
- ^ Levin MJ; Cai GY; Manchak MD; Pizer LI (June 2003). "Varicella-zoster virus DNA in cells isolated from human trigeminal ganglia". J. Virol. 77 (12): 6979–87. doi:10.1128/jvi.77.12.6979-6987.2003. PMC 156183. PMID 12768016.
- ^ Hanani M (February 2010). "Satellite glial cells: more than just 'rings around the neuron'". Neuron Glia Biol. 6 (1): 1–2. doi:10.1017/S1740925X10000104. PMID 20604976.