Serum amyloid A

Human Serum amyloid A1
Identifiers
SymbolSAA1
NCBI gene6288
HGNC10513
OMIM104750
RefSeqNM_199161
UniProtP0DJI8
Other data
LocusChr. 11 p15.1
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StructuresSwiss-model
DomainsInterPro
Human Serum amyloid A2
Identifiers
SymbolSAA2
NCBI gene6289
HGNC10514
OMIM104751
RefSeqNM_030754
UniProtP02735
Other data
LocusChr. 11 p15.1-p14
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StructuresSwiss-model
DomainsInterPro
Human Serum amyloid A3, pseudogene
Identifiers
SymbolSAA3P
Alt. symbolsSAA3
NCBI gene6290
HGNC10515
UniProtP22614
Other data
LocusChr. 11 p15.1-p14
Search for
StructuresSwiss-model
DomainsInterPro
Human Serum amyloid A4
Identifiers
SymbolSAA4
Alt. symbolsC-SAA
NCBI gene6291
HGNC10516
OMIM104752
RefSeqNM_006512
UniProtP35542
Other data
LocusChr. 11 p15.1-p14
Search for
StructuresSwiss-model
DomainsInterPro

Serum amyloid A (SAA) proteins are a family of apolipoproteins associated with high-density lipoprotein (HDL) in plasma. Different isoforms of SAA are expressed constitutively (constitutive SAAs) at different levels or in response to inflammatory stimuli (acute phase SAAs). These proteins are produced predominantly by the liver.[1]

  1. ^ Uhlar CM, Whitehead AS (October 1999). "Serum amyloid A, the major vertebrate acute-phase reactant". European Journal of Biochemistry. 265 (2): 501–23. doi:10.1046/j.1432-1327.1999.00657.x. PMID 10504381.
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