Quinupristin/dalfopristin

Quinupristin/dalfopristin
Quinupristin (top) and dalfopristin (bottom)
Combination of
QuinupristinStreptogramin antibiotic
DalfopristinStreptogramin antibiotic
Clinical data
Pregnancy
category
  • AU: B3
  • B (U.S.)
Routes of
administration
IV
ATC code
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
 NY (what is this?)  (verify)

Quinupristin/dalfopristin, or quinupristin-dalfopristin, (pronunciation: kwi NYOO pris tin / dal FOE pris tin) (trade name Synercid) is a combination of two antibiotics used to treat infections by staphylococci and by vancomycin-resistant Enterococcus faecium.

Quinupristin and dalfopristin are both streptogramin antibiotics, derived from pristinamycin. Quinupristin is derived from pristinamycin IA; dalfopristin from pristinamycin IIA. They are combined in a weight-to-weight ratio of 30% quinupristin to 70% dalfopristin. Discontinued 2022, there are no other manufacturers of this medication.