Syringocystadenoma papilliferum
| Syringocystadenoma papilliferum | |
|---|---|
| Other names | Syringadenoma papilliferum, Fistulous vegetative verrucous hydradenoma, Naevus syringocystadenomatosus papilliferus, Papillary syringocystadenoma, and SCAP. |
| An example of a syringocystadenoma papilliferum | |
| Specialty | Dermatology |
| Usual onset | Childhood, Neonatal, Infancy, Adolescent.[1] |
| Causes | Genetic.[2] |
| Diagnostic method | Skin biopsy.[3] |
| Differential diagnosis | Hidradenoma papilliferum, Papillary eccrine adenoma, Warty dyskeratoma, Tubular apocrine adenoma, Syringocystadenocarcinoma papilliferum.[3] |
| Treatment | Surgical excision.[3] |
Syringocystadenoma papilliferum is a rare non-malignant adnexal neoplasm that develops from apocrine or eccrine sweat glands and can be identified histologically by cystic, papillary, and ductal invaginations into the dermis lined by double-layered outer cuboidal and luminal high columnar epithelium and connected to the epidermis.[1]
Lesions have a heterogeneous, non-distinctive appearance that ranges from skin-colored to pink-colored papules or plaques. Typically, lesions form in the head and neck area.[1]
Syringocystadenoma papilliferum can develop de-novo or within a nevus sebaceous.[4] Syringocystadenoma papilliferum tends to be seen in children. It is present at birth in approximately 50% of individuals affected, and it develops before puberty in the remaining 15%-30%.[4]
- ^ a b c "Syringocystadenoma papilliferum". Orphanet. Retrieved 5 October 2023.
- ^ "Syringocystadenoma papilliferum — About the Disease — Genetic and Rare Diseases Information Center". rarediseases.info.nih.gov. Retrieved 2023-10-05.
- ^ a b c "Syringocystadenoma papilliferum". Pathology Outlines. March 10, 2022. Retrieved October 5, 2023.
- ^ a b Sangma, Mima Maychet B. (2013). "Syringocystadenoma Papilliferum of the Scalp in an Adult Male – A Case Report". Journal of Clinical and Diagnostic Research. 7 (4): 742–743. doi:10.7860/jcdr/2013/5452.2900. ISSN 2249-782X. PMC 3644463. PMID 23730665.