Systemic inflammatory response syndrome

This article is about Systemic inflammatory response syndrome. For the novel illnesses similar to the Kawasaki disease that has been observed in children possibly linked with COVID-19, see Paediatric multisystem inflammatory syndrome.
See also: Septic shock
Systemic inflammatory response syndrome
SpecialtyImmunology
ComplicationsAcute kidney injury, shock, septic shock, sepsis, multiple organ failure

In immunology, systemic inflammatory response syndrome (SIRS) is an inflammatory state affecting the whole body.[1] It is the body's response to an infectious or noninfectious insult. Although the definition of SIRS refers to it as an "inflammatory" response, it actually has pro- and anti-inflammatory components.

  1. ^ Jaffer U, Wade RG, Gourlay T (2010). "Cytokines in the systemic inflammatory response syndrome: a review". HSR Proc Intensive Care Cardiovasc Anesth. 2 (3): 161–75. ISSN 2037-0504. PMC 3484588. PMID 23441054.
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