Thioproperazine

Thioproperazine
Clinical data
Trade names	Majeptil
ATC code	N05AB08 (WHO) ;
Legal status
Legal status	BR: Class C1 (Other controlled substances);
Identifiers
	IUPAC name N,N-dimethyl-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine-2-carboxamide;
CAS Number	316-81-4;
PubChem CID	9429;
DrugBank	DB01622;
ChemSpider	9058;
UNII	YJ050AQ56X;
KEGG	D08585;
ChEBI	CHEBI:59120;
ChEMBL	ChEMBL609109;
CompTox Dashboard (EPA)	DTXSID1023655 ;
ECHA InfoCard	100.005.695
Chemical and physical data
Formula	C22H30N4O2S2
Molar mass	446.63 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)S(=O)(=O)N(C)C;
	InChI InChI=1S/C22H30N4O2S2/c1-23(2)30(27,28)18-9-10-22-20(17-18)26(19-7-4-5-8-21(19)29-22)12-6-11-25-15-13-24(3)14-16-25/h4-5,7-10,17H,6,11-16H2,1-3H3; Key:VZYCZNZBPPHOFY-UHFFFAOYSA-N;

Thioproperazine, sold under the brand name Majeptil, is a typical antipsychotic of the phenothiazine group which is used as a tranquilizer, antiemetic, sedative, and in the treatment of schizophrenia and manic phase of bipolar disorder.^[2]^[3]^[4]^[5] Majeptil is available in 10 mg tablets.^[6]

^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
^ Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 1019–. ISBN 978-3-88763-075-1.
^ Morton IK, Hall JM (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 272–. ISBN 978-94-011-4439-1.
^ "Phenothiazines (Systemic)". Drugs.com.
^ "Thioproperazine - Oral". Retrieved 2018-09-16.
^ "Thioproperazine". www.drugbank.ca. Retrieved 2018-09-16.