Toltrazuril

Toltrazuril
Clinical data
Trade names	Baycox, Tolcox
AHFS/Drugs.com	International Drug Names
ATCvet code	QP51BC01 (WHO) QP51BC51 (WHO);
Legal status
Legal status	CA: ℞-only;
Identifiers
	IUPAC name 1-methyl-3-[3-methyl-4-[4-(trifluoromethylthio)phenoxy]phenyl]-1,3,5-triazinane-2,4,6-trione;
CAS Number	69004-03-1 ;
PubChem CID	68591;
ChemSpider	61859 ;
UNII	QVZ3IAR3JS;
KEGG	D06187 ;
ChEMBL	ChEMBL2104931 ;
CompTox Dashboard (EPA)	DTXSID90219063 ;
ECHA InfoCard	100.132.547
Chemical and physical data
Formula	C18H14F3N3O4S
Molar mass	425.38 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC1=C(C=CC(=C1)N2C(=O)NC(=O)N(C2=O)C)OC3=CC=C(C=C3)SC(F)(F)F;
	InChI InChI=1S/C18H14F3N3O4S/c1-10-9-11(24-16(26)22-15(25)23(2)17(24)27)3-8-14(10)28-12-4-6-13(7-5-12)29-18(19,20)21/h3-9H,1-2H3,(H,22,25,26) ; Key:OCINXEZVIIVXFU-UHFFFAOYSA-N ;
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Toltrazuril is an antiparasitic medication used primarily to treat coccidiosis in animals. Coccidiosis is a parasitic disease caused by coccidia, which are microscopic, spore-forming, single-celled obligate intracellular parasites belonging to the apicomplexan class Conoidasida.^[1]^[2]^[3]

^ Diaferia M, Veronesi F, Morganti G, Nisoli L, Fioretti DP (August 2013). "Efficacy of toltrazuril 5 % suspension (Baycox®, Bayer) and diclazuril (Vecoxan®, Janssen-Cilag) in the control of Eimeria spp. in lambs". Parasitology Research. 112 (Suppl 1): 163–168. doi:10.1007/s00436-013-3440-1. PMID 23756962.
^ "Toltrazuril - referral". European Medicines Agency. Retrieved 2024-07-01.
^ Hawkins MG (January 2014). "Advances in exotic mammal clinical therapeutics". Journal of Exotic Pet Medicine. 23 (1): 39–49. doi:10.1053/j.jepm.2013.11.006. Toltrazuril, a broad-spectrum anticoccidial drug, is effective against both schizont and gamont stages of Eimeria spp.