Transient acantholytic dermatosis

Grover's disease
Other namesbenign papular acantholytic dermatosis,[1] transient acantholytic dermatosis,[1] persistent acantholytic dermatosis[1]
Micrograph of transient acantholytic dermatosis, showing subcorneal separation and acantholysis. H&E stain.
SpecialtyDermatology 

Grover's disease (GD) is a polymorphic, pruritic, papulovesicular dermatosis characterized histologically by acantholysis[2]: 529  with or without dyskeratosis.[3] Once confirmed, most cases of Grover's disease last six to twelve months, which is why it was originally called "transient". However it may last much longer. Nevertheless, it is not to be confused with relapsing linear acantholytic dermatosis.

  1. ^ a b c Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
  2. ^ Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.
  3. ^ Scheinfeld NS, Mones J (2006). "Seasonal variation of transient acantholytic dyskeratosis (Grover's disease)". J Am Acad Dermatol. 55 (2): 263–8. doi:10.1016/j.jaad.2006.01.029. PMID 16844509.