Yellow fever vaccine
Yellow fever vaccine vials (Brazil) | |
| Vaccine description | |
|---|---|
| Target | Yellow fever |
| Vaccine type | Attenuated |
| Clinical data | |
| Trade names | YF-Vax, Stamaril |
| Other names | 17D vaccine |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a607030 |
| Pregnancy category |
|
| Routes of administration | Subcutaneous |
| ATC code | |
| Legal status | |
| Legal status | |
| Identifiers | |
| ChemSpider |
|
| UNII | |
| (what is this?) (verify) | |
Yellow fever vaccine is a vaccine that protects against yellow fever.[4] Yellow fever is a viral infection that occurs in Africa and South America.[4] Most people begin to develop immunity within ten days of vaccination and are 99% protected within one month, and this appears to be lifelong.[4] The vaccine can be used to control outbreaks of disease.[4] It is given either by injection into a muscle or just under the skin.[4]
The World Health Organization (WHO) recommends routine immunization in all countries where the disease is common.[4] This should typically occur between nine and twelve months of age.[4] Those traveling to areas where the disease occurs should also be immunized.[4] Additional doses after the first are generally not needed.[5]
The yellow fever vaccine is generally safe.[4] This includes in those with HIV infection but without symptoms.[4] Mild side effects may include headache, muscle pains, pain at the injection site, fever, and rash.[4] Severe allergies occur in about eight per million doses, serious neurological problems occur in about four per million doses, and organ failure occurs in about three per million doses.[4] It appears to be safe in pregnancy and is therefore recommended among those who will be potentially exposed.[4] It should not be given to those with very poor immune function.[6]
Yellow fever vaccine came into use in 1938.[7] It is on the World Health Organization's List of Essential Medicines.[8][9] The vaccine is made from weakened yellow fever virus.[4] Some countries require a yellow fever vaccination certificate before entry from a country where the disease is common.[4]
- ^ Use During Pregnancy and Breastfeeding
- ^ "Stamaril powder and solvent for suspension for injection in pre-filled syringe - Summary of Product Characteristics (SmPC)". (emc). 9 September 2019. Retrieved 28 December 2019.
- ^ "YF-Vax". U.S. Food and Drug Administration (FDA). 6 August 2019. Archived from the original on 19 October 2020. Retrieved 28 December 2019.
- ^ a b c d e f g h i j k l m n o World Health Organization (July 2013). "Vaccines and vaccination against yellow fever. WHO position paper -- June 2013". Weekly Epidemiological Record. 88 (27): 269–283. hdl:10665/242089. PMID 23909008.
- ^ Staples JE, Bocchini JA, Rubin L, Fischer M (June 2015). "Yellow Fever Vaccine Booster Doses: Recommendations of the Advisory Committee on Immunization Practices, 2015". MMWR. Morbidity and Mortality Weekly Report. 64 (23): 647–650. PMC 4584737. PMID 26086636.
- ^ "Yellow Fever Vaccine". Centers for Disease Control and Prevention (CDC). 13 December 2011. Archived from the original on 9 December 2015. Retrieved 15 December 2015.
- ^ Norrby E (November 2007). "Yellow fever and Max Theiler: the only Nobel Prize for a virus vaccine". The Journal of Experimental Medicine. 204 (12): 2779–2784. doi:10.1084/jem.20072290. PMC 2118520. PMID 18039952.
- ^ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
- ^ World Health Organization (2021). World Health Organization model list of essential medicines: 22nd list (2021). Geneva: World Health Organization. hdl:10665/345533. WHO/MHP/HPS/EML/2021.02.