4-Hydroxyamphetamine

Hydroxyamphetamine
INN: Hydroxyamfetamine
Clinical data
Trade namesParedrine, Paremyd, Pedrolon, Mycadrine, Paredrinex, others
Other names4-Hydroxyamphetamine; 4-HA; Hydroxyamfetamine; Oxamphetamine; Norpholedrine; para-Hydroxyamphetamine; PHA; α-Methyltyramine; Methyltyramine, Hydroxyamphetamine (USAN US)
Routes of
administration		Eye drops
ATC code
  • None
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
IUPAC name
  • 4-(2-aminopropyl)phenol
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.002.866
Chemical and physical data
FormulaC9H13NO
Molar mass151.209 g·mol−1
3D model (JSmol)
SMILES
  • NC(C)Cc1ccc(O)cc1
InChI
  • InChI=1S/C9H13NO/c1-7(10)6-8-2-4-9(11)5-3-8/h2-5,7,11H,6,10H2,1H3 Y
  • Key:GIKNHHRFLCDOEU-UHFFFAOYSA-N Y
  (verify)

Hydroxyamphetamine, also known as 4-hydroxyamphetamine or norpholedrine and sold under the brand names Paredrine and Paremyd among others, is a sympathomimetic medication used in eye drops to dilate the pupil for eye examinations.[1][2][3][4]

Hydroxyamfetamine acts as a norepinephrine releasing agent and hence is an indirectly acting sympathomimetic.[5][6] It is a substituted phenethylamine and amphetamine.[4]

Hydroxyamphetamine appeared to remain marketed only in the Czech Republic as of 2004.[3]

  1. ^ Cite error: The named reference Elks2014 was invoked but never defined (see the help page).
  2. ^ Cite error: The named reference MortonHall2012 was invoked but never defined (see the help page).
  3. ^ a b Cite error: The named reference IndexNominum2004 was invoked but never defined (see the help page).
  4. ^ a b Cite error: The named reference DrugBank was invoked but never defined (see the help page).
  5. ^ Cite error: The named reference Lepore1985 was invoked but never defined (see the help page).
  6. ^ Cite error: The named reference Cho1978 was invoked but never defined (see the help page).
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