AMELY

AMELY
Identifiers
Aliases	AMELY, AMGL, AMGY, amelogenin, Y-linked, amelogenin Y-linked
External IDs	OMIM: 410000; MGI: 88005; HomoloGene: 47996; GeneCards: AMELY; OMA:AMELY - orthologs
Gene location (Human)
Chr.	Y chromosome (human)
End	6,911,752 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	167,970,196 bp
RNA expression pattern
	Top expressed in
	testicle; ; gonad; ; sural nerve; ; placenta; ; Ventricular system of neuraxis; ; ventricular zone; ; thyroid gland; ; left lobe of thyroid gland; ; hepatobiliary system; ; pancreas;
	Top expressed in
	molar; ; embryo; ; mandibular molars; ; nucleus pulposus; ; sexually immature organism; ; temporal muscle; ; ascending aorta; ; aortic valve; ; olfactory epithelium; ; tibiofemoral joint;
	More reference expression data
	n/a
Gene ontology
Molecular function	structural constituent of tooth enamel;
Cellular component	extracellular matrix; extracellular region; collagen-containing extracellular matrix;
Biological process	multicellular organism development; biomineral tissue development; tooth mineralization;
	Sources:Amigo / QuickGO
Orthologs
	266
	11704
	ENSG00000099721
	ENSMUSG00000031354
	Q99218
	P63277
	NM_001143; NM_001364814
	NM_001081978; NM_009666; NM_001290371
	NP_001134; NP_001351743
	NP_001075447; NP_001277300; NP_033796
	Wikidata
View/Edit Human	View/Edit Mouse

Amelogenin, Y isoform is a protein that in humans is encoded by the AMELY gene.^[5]^[6] AMELY is located on the Y chromosome and encodes a form of amelogenin. Amelogenin is an extracellular matrix protein involved in biomineralization during tooth enamel development.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000099721 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031354 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nakahori Y, Takenaka O, Nakagome Y (February 1991). "A human X-Y homologous region encodes "amelogenin"". Genomics. 9 (2): 264–9. doi:10.1016/0888-7543(91)90251-9. PMID 2004775.
^ "Entrez Gene: amelogenin".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000099721 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031354 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid2004775-5] Nakahori Y, Takenaka O, Nakagome Y (February 1991). "A human X-Y homologous region encodes "amelogenin"". Genomics. 9 (2): 264–9. doi:10.1016/0888-7543(91)90251-9. PMID 2004775.

[entrez-6] "Entrez Gene: amelogenin".

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