Ameloblastin

AMBN
Identifiers
Aliases	AMBN, AI1F, Sheathlin, ameloblastin
External IDs	OMIM: 601259; MGI: 104655; HomoloGene: 7625; GeneCards: AMBN; OMA:AMBN - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	70,607,288 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	88,616,390 bp
RNA expression pattern
	Top expressed in
	testicle; ; putamen; ; caudate nucleus; ; gonad; ; nucleus accumbens; ; islet of Langerhans; ; Epithelium of choroid plexus; ; ventricular zone; ; prefrontal cortex; ; mesencephalon;
	Top expressed in
	molar; ; membranous bone; ; maxilla; ; sexually immature organism; ; mandible; ; inner enamel epithelium; ; fossa; ; lumbar subsegment of spinal cord; ; incisor; ; dermis;
	More reference expression data
	n/a
Gene ontology
Molecular function	structural constituent of tooth enamel; growth factor activity; protein binding;
Cellular component	extracellular region; endoplasmic reticulum lumen;
Biological process	odontogenesis of dentin-containing tooth; biomineral tissue development; cell adhesion; cell population proliferation; post-translational protein modification; regulation of signaling receptor activity; regulation of cell population proliferation; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	258
	11698
	ENSG00000178522
	ENSMUSG00000029288
	Q9NP70
	O55189
	NM_016519
	NM_009664; NM_001303431
	NP_057603
	NP_001290360; NP_033794
	Wikidata
View/Edit Human	View/Edit Mouse

Ameloblastin (abbreviated AMBN and also known as sheathlin or amelin) is an enamel matrix protein that in humans is encoded by the AMBN gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000178522 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000029288 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Ameloblastin (enamel matrix protein)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000178522 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000029288 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Ameloblastin (enamel matrix protein)".

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