Bromoform
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A bottle of bromoform with some in the adjacent beaker
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| Names | |||
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| Preferred IUPAC name
Tribromomethane[1] | |||
| Other names | |||
| Identifiers | |||
CAS Number
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3D model (JSmol)
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| Abbreviations |
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Beilstein Reference
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1731048 | ||
| ChEBI | |||
| ChEMBL | |||
| ChemSpider | |||
| DrugBank | |||
| ECHA InfoCard | 100.000.777 | ||
| EC Number |
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Gmelin Reference
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49500 | ||
| KEGG | |||
| MeSH | bromoform | ||
PubChem CID
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| RTECS number |
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| UNII | |||
| UN number | 2515 | ||
CompTox Dashboard (EPA)
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InChI
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SMILES
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| Properties | |||
Chemical formula
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CHBr3 | ||
| Molar mass | 252.731 g·mol−1 | ||
| Appearance | Colorless liquid | ||
| Density | 2.89 g/cm3 | ||
| Melting point | 8.69 °C; 47.64 °F; 281.84 K | ||
| Boiling point | 149.40 °C; 300.92 °F; 422.55 K | ||
Solubility in water
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3.2 g L−1 (at 30 °C) | ||
| log P | 2.435 | ||
| Vapor pressure | 670 Pa (at 20.0 °C) | ||
Henry's law
constant (kH) |
17 μmol Pa−1 kg−1 | ||
| Acidity (pKa) | 13.7 | ||
Magnetic susceptibility (χ)
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−82.60·10−6 cm3/mol | ||
Refractive index (nD)
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1.595 | ||
| Thermochemistry | |||
Heat capacity (C)
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130.5 J K−1 mol−1 | ||
Std enthalpy of
formation (ΔfH⦵298) |
6.1–12.7 kJ mol−1 | ||
Std enthalpy of
combustion (ΔcH⦵298) |
−549.1–−542.5 kJ mol−1 | ||
| Hazards | |||
| GHS labelling: | |||
Pictograms
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Signal word
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Danger | ||
Hazard statements
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H302, H315, H319, H331, H411 | ||
Precautionary statements
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P261, P273, P305+P351+P338, P311 | ||
| NFPA 704 (fire diamond) | |||
| Lethal dose or concentration (LD, LC): | |||
LD50 (median dose)
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933.0 mg kg−1 (oral, rat) | ||
LDLo (lowest published)
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1400 mg/kg (mouse, oral) 1147 mg/kg (rat, oral)[4] | ||
LC50 (median concentration)
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1151 ppm (mammal)[4] | ||
LCLo (lowest published)
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4282 ppm (rat, 4 hr) 7000 ppm (dog, 1 hr)[4] | ||
| NIOSH (US health exposure limits): | |||
PEL (Permissible)
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TWA 0.5 ppm (5 mg/m3) [skin][2] | ||
REL (Recommended)
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TWA 0.5 ppm (5 mg/m3) [skin][2] | ||
IDLH (Immediate danger)
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850 ppm[2] | ||
| Related compounds | |||
Related alkanes
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| Supplementary data page | |||
| Bromoform (data page) | |||
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
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Bromoform is an organic compound with the chemical formula CHBr3. It is a colorless liquid at room temperature, with a high refractive index and a very high density. Its sweet odor is similar to that of chloroform. It is one of the four haloforms, the others being fluoroform, chloroform, and iodoform. It is a brominated organic solvent. Currently its main use is as a laboratory reagent. It is very slightly soluble in water (one part bromoform in 800 parts water) and is miscible with alcohol, benzene, chloroform, ether, petroleum ether, acetone and oils.
- ^ a b Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. p. 661. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4.
The retained names 'bromoform' for HCBr3, 'chloroform' for HCCl3, and 'iodoform' for HCI3 are acceptable in general nomenclature. Preferred IUPAC names are substitutive names.
- ^ a b c d NIOSH Pocket Guide to Chemical Hazards. "#0066". National Institute for Occupational Safety and Health (NIOSH).
- ^ Rumble, John (18 June 2018). CRC Handbook of Chemistry and Physics. CRC Press. pp. 3–50. ISBN 9781138561632.
- ^ a b c "Bromoform". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).