C4A

C4A
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1HZF, 4FXG, 4FXK, 4XAM
Identifiers
Aliases	C4A, C4, C4A2, C4A3, C4A4, C4A6, C4AD, C4S, CO4, CPAMD2, RG, complement component 4A (Rodgers blood group), complement C4A (Rodgers blood group)
External IDs	OMIM: 120810; MGI: 88228; HomoloGene: 36030; GeneCards: C4A; OMA:C4A - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	32,002,681 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	34,962,856 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; right adrenal cortex; ; left adrenal cortex; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; right ovary; ; tibial nerve; ; left ovary; ; anterior pituitary; ; spleen;
	Top expressed in
	zone of skin; ; adrenal gland; ; white adipose tissue; ; synovial joint; ; ankle joint; ; spleen; ; liver; ; uterus; ; esophagus; ; urinary bladder;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	endopeptidase inhibitor activity; complement component C1q complex binding; serine-type endopeptidase activity;
Cellular component	extracellular region; plasma membrane; extracellular exosome; blood microparticle; cell projection; dendrite; cell junction; synapse; axon; soma; extracellular space; endoplasmic reticulum lumen;
Biological process	complement activation; inflammatory response; positive regulation of apoptotic cell clearance; regulation of complement activation; negative regulation of endopeptidase activity; complement activation, classical pathway; immune system process; innate immune response; proteolysis; post-translational protein modification;
	Sources:Amigo / QuickGO
Orthologs
	720
	12268
	ENSG00000244207; ENSG00000206340; ENSG00000244731; ENSG00000227746
	ENSMUSG00000073418
	P0C0L4
	P01029
	NM_001252204; NM_007293
	NM_009780
	NP_001239133; NP_009224
	NP_033910
	Wikidata
View/Edit Human	View/Edit Mouse

Complement C4-A is a kind of the Complement component 4 protein that in humans is encoded by the C4A gene.^[5]

^ ^a ^b ^c ENSG00000206340, ENSG00000244731, ENSG00000227746 GRCh38: Ensembl release 89: ENSG00000244207, ENSG00000206340, ENSG00000244731, ENSG00000227746 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000073418 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: C4A complement component 4A (Rodgers blood group)".

[refGRCh38Ensembl-1] ENSG00000206340, ENSG00000244731, ENSG00000227746 GRCh38: Ensembl release 89: ENSG00000244207, ENSG00000206340, ENSG00000244731, ENSG00000227746 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000073418 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: C4A complement component 4A (Rodgers blood group)".

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