CYP2J2

CYP2J2
Identifiers
Aliases	CYP2J2, CPJ2, CYPIIJ2, cytochrome P450 family 2 subfamily J member 2
External IDs	OMIM: 601258; MGI: 1270148; HomoloGene: 68091; GeneCards: CYP2J2; OMA:CYP2J2 - orthologs
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	96,441,898 bp
RNA expression pattern
	n/a
	Top expressed in
	saccule; ; pyloric antrum; ; epithelium of small intestine; ; epithelium of stomach; ; jejunum; ; mucous cell of stomach; ; otic vesicle; ; nose; ; olfactory epithelium; ; duodenum;
	More reference expression data
Gene ontology
Molecular function	iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; metal ion binding; arachidonic acid 14,15-epoxygenase activity; heme binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; arachidonic acid 11,12-epoxygenase activity; oxidoreductase activity; aromatase activity; linoleic acid epoxygenase activity; monooxygenase activity; arachidonic acid epoxygenase activity; steroid hydroxylase activity;
Cellular component	organelle membrane; endoplasmic reticulum membrane; membrane; intracellular membrane-bounded organelle; endoplasmic reticulum; extracellular exosome; cytoplasm;
Biological process	linoleic acid metabolic process; regulation of heart contraction; epoxygenase P450 pathway; icosanoid metabolic process; xenobiotic metabolic process; organic acid metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	1573
	13110
	ENSG00000134716
	ENSMUSG00000052914
	P51589
	O54750
	n/a
	NM_010008
	NP_000766
	NP_034138
	Wikidata
View/Edit Human	View/Edit Mouse

Cytochrome P450 2J2 (CYP2J2) is a protein that in humans is encoded by the CYP2J2 gene.^[4]^[5] CYP2J2 is a member of the cytochrome P450 superfamily of enzymes. The enzymes are oxygenases which catalyze many reactions involved in the metabolism of drugs and other xenobiotics) as well as in the synthesis of cholesterol, steroids and other lipids.

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000052914 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ma J, Ramachandran S, Fiedorek FT, Zeldin DC (Apr 1998). "Mapping of the CYP2J cytochrome P450 genes to human chromosome 1 and mouse chromosome 4". Genomics. 49 (1): 152–155. doi:10.1006/geno.1998.5235. PMID 9570962.
^ "Entrez Gene: CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2".

[refGRCm38Ensembl-1] GRCm38: Ensembl release 89: ENSMUSG00000052914 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[Ma_1998-4] Ma J, Ramachandran S, Fiedorek FT, Zeldin DC (Apr 1998). "Mapping of the CYP2J cytochrome P450 genes to human chromosome 1 and mouse chromosome 4". Genomics. 49 (1): 152–155. doi:10.1006/geno.1998.5235. PMID 9570962.

[entrez-5] "Entrez Gene: CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2".

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